J
Juliane G. Strauss
Researcher at University of Graz
Publications - 18
Citations - 3726
Juliane G. Strauss is an academic researcher from University of Graz. The author has contributed to research in topics: Adipose tissue & Lipoprotein lipase. The author has an hindex of 14, co-authored 18 publications receiving 3458 citations. Previous affiliations of Juliane G. Strauss include Graz University of Technology.
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Journal ArticleDOI
Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase
Robert Zimmermann,Juliane G. Strauss,Guenter Haemmerle,Gabriele Schoiswohl,Ruth Birner-Gruenberger,Monika Riederer,Achim Lass,Georg Neuberger,Frank Eisenhaber,Albin Hermetter,Rudolf Zechner +10 more
TL;DR: It is reported that a second enzyme, adipose triglyceride lipase (ATGL), catalyzes the initial step in triglyceride hydrolysis, and it is interesting that ATGL contains a “patatin domain” common to plant acyl-hydrolases.
Journal ArticleDOI
Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome.
Achim Lass,Robert Zimmermann,Guenter Haemmerle,Monika Riederer,Gabriele Schoiswohl,Martina Schweiger,Petra C. Kienesberger,Juliane G. Strauss,Gregor Gorkiewicz,Rudolf Zechner +9 more
TL;DR: Exercise of functional CGI-58 in CDS fibroblasts restores lipolysis and reverses the abnormal TG accumulation typical for CDS, establishing an important biochemical function for CGI- 58 in the lipolytic degradation of fat.
Journal ArticleDOI
Lipolysis: pathway under construction.
TL;DR: Adipose triglyceride lipase represents a novel type of ‘patatin domain-containing’ triacylglycerol hydrolase that is more closely related to plant lipases than to other known mammalian metabolic triacyLglycerl hydrolases, and requires a revision of the concept that hormone-sensitive lipase is the only enzyme involved in the lipolysis of adipose tissue triglycerides.
Journal ArticleDOI
Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle
Guenter Haemmerle,Robert Zimmermann,Juliane G. Strauss,Dagmar Kratky,Monika Riederer,Gabriele Knipping,Rudolf Zechner +6 more
TL;DR: It is demonstrated that HSL deficiency markedly affects the metabolism of TG-rich lipoproteins by the coordinate down-regulation of VLDL synthesis and up- regulation of LPL in muscle and white adipose tissue, which result in an “anti-atherogenic” lipoprotein profile.
Journal ArticleDOI
Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormone-sensitive lipase-deficient white adipose tissue
Robert Zimmermann,Guenter Haemmerle,Elke M. Wagner,Juliane G. Strauss,Dagmar Kratky,Rudolf Zechner +5 more
TL;DR: Results establish that in the absence of HSL, the reduced NEFA production is counteracted by a drastic reduction of NEFA reesterification that provides sufficient quantities ofNEFA for release into the circulation.