J
Julio S. Rufas
Researcher at Autonomous University of Madrid
Publications - 85
Citations - 2653
Julio S. Rufas is an academic researcher from Autonomous University of Madrid. The author has contributed to research in topics: Meiosis & Synapsis. The author has an hindex of 29, co-authored 85 publications receiving 2435 citations. Previous affiliations of Julio S. Rufas include Spanish National Research Council.
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Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I
Ignacio Prieto,José A. Suja,Nieves Pezzi,Leonor Kremer,Carlos Martínez-A,Julio S. Rufas,José Luis Barbero +6 more
TL;DR: It is shown that STAG3 has a role in sister chromatid arm cohesion during mammalian meiosis I and that it interacts with the structural maintenance chromosome proteins SMC1 and SMC3, which have been reported to be subunits of the mitotic cohesin complex.
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Involvement of the cohesin Rad21 and SCP3 in monopolar attachment of sister kinetochores during mouse meiosis I.
María Teresa Parra,Alberto Viera,Rocío Gómez,Jesús Page,Ricardo Benavente,Juan Luis Santos,Julio S. Rufas,José A. Suja +7 more
TL;DR: It is hypothesised that Rad21, and the superimposed SCP3 and SCP2, are involved in the monopolar attachment of sister kinetochores during meiosis I, and are not responsible for the maintenance of sister-chromatid centromere cohesion during meiotic II as previously suggested.
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Squash procedure for protein immunolocalization in meiotic cells.
TL;DR: A novel squash procedure of cell preparation for protein immunolabelling of different meiotic stages that is an alternative to both cryosectioning and whole spreading procedures and suitable for three-dimensional analyses and proved to be reliable in a wide range of systems including insects and mammals.
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A High Incidence of Meiotic Silencing of Unsynapsed Chromatin Is Not Associated with Substantial Pachytene Loss in Heterozygous Male Mice Carrying Multiple Simple Robertsonian Translocations
Marcia Manterola,Jesús Page,Chiara Vasco,Soledad Berríos,María Teresa Parra,Alberto Viera,Julio S. Rufas,Maurizio Zuccotti,Silvia Garagna,Raúl Fernández-Donoso +9 more
TL;DR: It is proposed that a low stringency of the pachytene checkpoint could help to increase the chances that spermatocytes with synaptic defects will complete meiotic divisions and differentiate into viable gametes, explaining the multitude of natural Robertsonian populations described in the mouse.
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CDK2 is required for proper homologous pairing, recombination and sex-body formation during male mouse meiosis
TL;DR: The data demonstrate an unpredicted participation of CDK2 in the accurate pairing and recombination between homologues during mammalian meiosis, leading to infertility in Cdk2–/– male mice.