J
Jun Chen
Researcher at Shanghai Jiao Tong University
Publications - 2300
Citations - 100809
Jun Chen is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 136, co-authored 1856 publications receiving 77368 citations. Previous affiliations of Jun Chen include Peking Union Medical College & Nankai University.
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Design of two 3D homochiral Co(II) metal–organic open frameworks by layered-pillar strategy: structure and properties
TL;DR: Two 3D homochiral metal-organic open frameworks were designed and fabricated in a layered-pillar fashion as discussed by the authors, and they show considerable hydrogen storage property with a fairly high affinity to H2 and prove to be homomorphic prous ferromagnet.
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Clearance of systemic hematologic tumors by venetoclax (Abt-199) and navitoclax.
Scott L. Ackler,Anatol Oleksijew,Jun Chen,Brenda Chyla,Jerry Clarin,Kelly Foster,Thomas McGonigal,Sasmita Mishra,Sally Schlessinger,Morey L. Smith,Stephen K. Tahir,Joel D. Leverson,Andrew J. Souers,Erwin R. Boghaert,Jonathan Hickson +14 more
TL;DR: It is shown that intravenous inoculation of engineered RS4;11 and Granta 519 bioluminescent reporter cell lines result in tumor engraftment of bone marrow and apoptosis induction and response of these systemically engrafted tumors to Bcl‐2 family inhibitors alone or in combination with standard‐of‐care agents could be monitored longitudinally with optical imaging, and was more accurately reflective of the observed clinical response.
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Experiment and numerical simulation on delamination during the laminated steel sheet forming processes.
TL;DR: In this paper, a step-bottom square cup drawing was used to study the delamination in the deep drawing of the laminated sheet metal in more complex stress state, and a nonlinear visco-elastic material model was applied to describe the mechanical behavior of polymer layer.
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Gabapentinoid Insensitivity after Repeated Administration is Associated with Down-Regulation of the α 2 δ-1 Subunit in Rats with Central Post-Stroke Pain Hypersensitivity
Yan Yang,Fei Yang,Fan Yang,Chun-Li Li,Yan Wang,Zhen Li,Yun-Fei Lu,Yao-Qing Yu,Han Fu,Ting He,Wei Sun,Rui-Rui Wang,Jun Chen +12 more
TL;DR: The present results suggest that the GBP receptor α2δ-1 is mainly expressed in thalamic neurons in which it is up-regulated in the early stage of CPSP but this is followed by dramatic down-regulation, which is likely associated with GBP insensitivity after long-term use.
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Supercritical CO2-constructed intralayer [Bi2O2]2+ structural distortion for enhanced CO2 electroreduction
Yannan Zhou,Pengfei Yan,Jun Jia,Suoying Zhang,Xiaoli Zheng,Li Zhang,Bin Zhang,Jun Chen,Weichang Hao,Gongji Chen,Qun Xu,Buxing Han +11 more
TL;DR: In this article, the authors achieved the intralayer [Bi2O2]2+ structural distortion by using supercritical CO2 as a solvent to reduce the number of interlayer chlorine atoms involved in the CO2 reduction reaction.