Jun He

TL;DR: This work summarizes the recent advances in PPIs modulators, including small molecules, peptides, and antibodies, hoping to provide some guidance to the design of novel drugs targeting PPIs in the future.

TL;DR: A comprehensive review of the structure, function and modulators of Sirtuins is presented, which is expected to be beneficial to relevant studies.

TL;DR: Findings on pathway‐ involved plant lectins are summarized to provide a comprehensive perspective for further elucidating their potential role as novel anti‐cancer drugs, with respect to both apoptosis and autophagy in cancer pathogenesis, and future therapy.

TL;DR: This review represents a renewal of previous works on the development of dual VEGFR and c-Met small molecule inhibitors as novel anti-cancer agents on the basis of the strong interest in these compounds.

TL;DR: The research status of 37 natural products that have been discovered to have significant anti-PD effects as well as their mode of action are reviewed to guide the design of novel therapeutic drugs in PD.