Jun Liu

TL;DR: A Bayesian model is introduced to integrate multiple independent microarray data sets from three recent genome-wide cell cycle studies on fission yeast and a novel Metropolis-Hastings group move is developed in order to facilitate an efficient Monte Carlo sampling from the joint posterior distribution.

TL;DR: The results indicated that genetic variation in SNCA may contribute to variability natural progression of PD and could possibly be used as a prognostic marker.

TL;DR: To facilitate the translation of iPSC technology to clinical practice, mRNA reprogramming method that generates transgene-free iPSCs is a safe and efficient method, eliminating bio-containment concerns associated with viral vectors, as well as the need for weeks of screening of cells to confirm that viral material has been completely eliminated during cell passaging.

TL;DR: The lifespan of GFF cell lines has a major effect on the efficiency to produce transgenic cloned goats, and the proliferative lifespan of primary cells may be used as a criterion to characterize the quality of cell lines for genetic modification and SCNT.

TL;DR: A novel model named as representative latent Dirichlet allocation (RLDA) topic model was applied to a corpus of more than 337,000 literatures of diabetes and obesity and extracted the significant relationships between them and other diseases such as Alzheimer’s disease, heart disease and tumor.