J
Jung-Hyun Lee
Researcher at Seoul National University
Publications - 256
Citations - 5900
Jung-Hyun Lee is an academic researcher from Seoul National University. The author has contributed to research in topics: Thermococcus & Biology. The author has an hindex of 38, co-authored 215 publications receiving 5045 citations. Previous affiliations of Jung-Hyun Lee include Kyung Hee University & Korean Ocean Research and Development Institute.
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Journal ArticleDOI
One-Step Sequence- and Ligation-Independent Cloning as a Rapid and Versatile Cloning Method for Functional Genomics Studies
Jae-Yeon Jeong,Hyung-Soon Yim,Ji-Young Ryu,Hyun Sook Lee,Jung-Hyun Lee,Dong-Seung Seen,Sung Gyun Kang +6 more
TL;DR: One-step sequence- and ligation-independent cloning (SLIC) is developed as a simple, cost-effective, time-saving, and versatile cloning method that achieves highly efficient and directional cloning.
Journal ArticleDOI
Minke whale genome and aquatic adaptation in cetaceans
Hyung-Soon Yim,Yun Sung Cho,Xuanmin Guang,Sung Gyun Kang,Jae Yeon Jeong,Sun Shin Cha,Hyun Myung Oh,Jae Hak Lee,Eun Chan Yang,Kae Kyoung Kwon,Yun Jae Kim,Tae Wan Kim,Wonduck Kim,Jeong Ho Jeon,Sang-Jin Kim,Dong Han Choi,Sungwoong Jho,Hak-Min Kim,Junsu Ko,Hyunmin Kim,Young Ah Shin,Hyun Ju Jung,Yuan Zheng,Zhuo Wang,Yan Chen,Ming Chen,Awei Jiang,Erli Li,Shu Zhang,Haolong Hou,Tae Hyung Kim,Lili Yu,Sha Liu,Kung Ahn,Jesse Cooper,Sin Gi Park,Chang Pyo Hong,Wook Jin,Heui Soo Kim,Chankyu Park,Kyooyeol Lee,Sung Chun,Phillip A. Morin,Stephen J. O'Brien,Hang Lee,Jumpei Kimura,Dae Yeon Moon,Andrea Manica,Jeremy S. Edwards,Byung Chul Kim,Sangsoo Kim,Jun Wang,Jong Bhak,Hyun Sook Lee,Jung-Hyun Lee +54 more
TL;DR: Overall the whale-genome sequences exhibited distinct features that are associated with the physiological and morphological changes needed for life in an aquatic environment, marked by resistance to physiological stresses caused by a lack of oxygen, increased amounts of reactive oxygen species and high salt levels.
Journal Article
Microbial Symbiosis in Marine Sponges
TL;DR: Sponges are host organisms for various symbiotic microorganisms such as archaea, bacteria, cyano-bacteria and microalgae, and sources of a wide variety of useful natural products like cyto-toxins, antifouling agents, antibiotics, and anti-inflammatory and antiviral compounds.
Journal ArticleDOI
Formate-driven growth coupled with H2 production
Yun Jae Kim,Hyun Sook Lee,Eun Sook Kim,Seung Seob Bae,Jae Kyu Lim,Rie Matsumi,Alexander V. Lebedinsky,T. G. Sokolova,Darya A. Kozhevnikova,Sun Shin Cha,Sang-Jin Kim,Kae Kyoung Kwon,Tadayuki Imanaka,Haruyuki Atomi,Elizaveta A. Bonch-Osmolovskaya,Jung-Hyun Lee,Sung Gyun Kang +16 more
TL;DR: Several hyperthermophilic archaea belonging to the Thermococcus genus are capable of formate-oxidizing, H2-producing growth and the biochemical basis of this ability is reported.
Journal ArticleDOI
The Complete Genome Sequence of Thermococcus onnurineus NA1 Reveals a Mixed Heterotrophic and Carboxydotrophic Metabolism
Hyun Sook Lee,Sung Gyun Kang,Seung Seob Bae,Jae Kyu Lim,Yona Cho,Yun Jae Kim,Jeong Ho Jeon,Sun Shin Cha,Kae Kyoung Kwon,Hyungtae Kim,Cheol-Joo Park,Heewook Lee,Seung Il Kim,Jongsik Chun,Rita R. Colwell,Sang-Jin Kim,Jung-Hyun Lee +16 more
TL;DR: The complete genome sequence and feature analysis of Thermococcus onnurineus NA1 isolated from a deep-sea hydrothermal vent area reveals clues to its physiology, providing the first genomic evidence for the carboxydotrophy in Thermitis.