Jungnam Joo

TL;DR: Performance of several approaches for testing association on the X chromosome are compared, and how departure from Hardy‐Weinberg equilibrium would affect type I error and power of these association tests using X‐linked SNPs is examined.

TL;DR: In a personalized medicine intervention, the minimum detectable difference used in sample size calculations is not a known quantity, but rather an unknown quantity that depends on the genetic makeup of the subjects enrolled, and it is recommended that they be monitored during the conduct of a personalized Medicine intervention.

TL;DR: The studies suggest that UGT1A1 may be the major gene with strong effects on bilirubin levels and the TA-repeat polymorphism might be the key polymorphism within the gene controlling bilirUBin levels.

TL;DR: The CardioGene Study is an ongoing study of restenosis in bare mental stents (BMS) for the treatment of coronary artery disease to understand the genetic determinants of the responses to vascular injury that result in the development of restanosis in some patients but not in others.

TL;DR: Preclinical data show plerixafor, in contrast with G-CSF, does not alter the phenotype and cytokine polarization of T cells, which raises the possibility that T cell–mediated immune sequelae of allogeneic transplantation in humans may differ when donor allografts are mobilized with plerxafor compared with G.CSF.