J
Junko Hirota
Researcher at Osaka University
Publications - 3
Citations - 348
Junko Hirota is an academic researcher from Osaka University. The author has contributed to research in topics: Histone H1 & APAF1. The author has an hindex of 3, co-authored 3 publications receiving 333 citations. Previous affiliations of Junko Hirota include Juntendo University.
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Journal ArticleDOI
Involvement of Histone H1.2 in Apoptosis Induced by DNA Double-Strand Breaks
Akimitsu Konishi,Akimitsu Konishi,Shigeomi Shimizu,Junko Hirota,Toshifumi Takao,Yuhong Fan,Yosuke Matsuoka,Lilin Zhang,Yoshihiro Yoneda,Yoshitaka Fujii,Arthur I. Skoultchi,Yoshihide Tsujimoto +11 more
TL;DR: The results indicate that histone H1.2 plays an important role in transmitting apoptotic signals from the nucleus to the mitochondria following DNA double-strand breaks, as well as that induced by TNF-alpha and UV irradiation.
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ε-N,N,N-Trimethyllysine-specific ions in matrix-assisted laser desorption/ionization-tandem mass spectrometry
TL;DR: During the measurements of the modified peptides, a novel fragmentation which involves the loss of trimethylamine from K(me3) was found, which was observed to produce ions separated by 59 Da from the conventional precursor ion or sequence ions, which would be useful for probing K( me3) units in the sequence.
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Identification of variant molecules of Bacillus thermoproteolyticus ferredoxin: crystal structure reveals bound coenzyme A and an unexpected [3Fe-4S] cluster associated with a canonical [4Fe-4S] ligand motif.
Tadayoshi Shirakawa,Yasuhiro Takahashi,Kei Wada,Junko Hirota,Toshifumi Takao,Daijiro Ohmori,Keiichi Fukuyama +6 more
TL;DR: During the purification of recombinant Bacillus thermoproteolyticus ferredoxin from Escherichia coli, it is noted that some Fe-S proteins were produced in relatively small amounts compared to the originally identified BtFd carrying a [4Fe-4S] cluster, suggesting covalent modification may have occurred in vivo.