Y
Yoshihide Tsujimoto
Researcher at Osaka University
Publications - 195
Citations - 35663
Yoshihide Tsujimoto is an academic researcher from Osaka University. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 88, co-authored 195 publications receiving 34311 citations. Previous affiliations of Yoshihide Tsujimoto include Boehringer Ingelheim & National Cancer Research Institute.
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Journal ArticleDOI
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
TL;DR: The results indicate that the Bcl-2 family of proteins bind to the VDAC in order to regulate the mitochondrial membrane potential and the release of cytochrome c during apoptosis.
Journal ArticleDOI
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes
Lorenzo Galluzzi,Lorenzo Galluzzi,Lorenzo Galluzzi,Stuart A. Aaronson,John M. Abrams,Emad S. Alnemri,David W. Andrews,Eric H. Baehrecke,Nicolas G. Bazan,Mikhail V. Blagosklonny,Klas Blomgren,Klas Blomgren,Christoph Borner,Dale E. Bredesen,Dale E. Bredesen,Catherine Brenner,Maria Castedo,Maria Castedo,Maria Castedo,John A. Cidlowski,Aaron Ciechanover,Gerald M. Cohen,V De Laurenzi,R De Maria,Mohanish Deshmukh,Brian David Dynlacht,Wafik S. El-Deiry,Richard A. Flavell,Richard A. Flavell,Simone Fulda,Carmen Garrido,Carmen Garrido,Pierre Golstein,Pierre Golstein,Pierre Golstein,Marie-Lise Gougeon,Douglas R. Green,Hinrich Gronemeyer,Hinrich Gronemeyer,Hinrich Gronemeyer,György Hajnóczky,J. M. Hardwick,Michael O. Hengartner,Hidenori Ichijo,Marja Jäättelä,Oliver Kepp,Oliver Kepp,Oliver Kepp,Adi Kimchi,Daniel J. Klionsky,Richard A. Knight,Sally Kornbluth,Sharad Kumar,Beth Levine,Beth Levine,Stuart A. Lipton,Enrico Lugli,Frank Madeo,Walter Malorni,Jean-Christophe Marine,Seamus J. Martin,Jan Paul Medema,Patrick Mehlen,Patrick Mehlen,Gerry Melino,Gerry Melino,Ute M. Moll,Ute M. Moll,Eugenia Morselli,Eugenia Morselli,Eugenia Morselli,Shigekazu Nagata,Donald W. Nicholson,Pierluigi Nicotera,Gabriel Núñez,Moshe Oren,Josef M. Penninger,Shazib Pervaiz,Marcus E. Peter,Mauro Piacentini,Jochen H. M. Prehn,Hamsa Puthalakath,Gabriel A. Rabinovich,Rosario Rizzuto,Cecília M. P. Rodrigues,David C. Rubinsztein,Thomas Rudel,Luca Scorrano,Hans-Uwe Simon,Hermann Steller,Hermann Steller,J. Tschopp,Yoshihide Tsujimoto,Peter Vandenabeele,Ilio Vitale,Ilio Vitale,Ilio Vitale,Karen H. Vousden,Richard J. Youle,Junying Yuan,Boris Zhivotovsky,Guido Kroemer,Guido Kroemer,Guido Kroemer +103 more
TL;DR: A nonexhaustive comparison of methods to detect cell death with apoptotic or nonapoptotic morphologies, their advantages and pitfalls is provided and the importance of performing multiple, methodologically unrelated assays to quantify dying and dead cells is emphasized.
Journal ArticleDOI
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
Takashi Nakagawa,Shigeomi Shimizu,Tetsuya Watanabe,Osamu Yamaguchi,Kinya Otsu,Hirotaka Yamagata,Hidenori Inohara,Takeshi Kubo,Yoshihide Tsujimoto +8 more
TL;DR: The results indicate that the CypD-dependent mPT regulates some forms of necrotic death, but not apoptotic death, as indicated by resistance to ischaemia/reperfusion-induced cardiac injury.
Journal ArticleDOI
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes.
Shigeomi Shimizu,Toku Kanaseki,Noboru Mizushima,Noboru Mizushima,Noboru Mizushima,Takeshi Mizuta,Satoko Arakawa-Kobayashi,Craig B. Thompson,Yoshihide Tsujimoto +8 more
TL;DR: Results indicate that the Bcl-2 family of proteins not only regulates apoptosis, but also controls non-apoptotic programmed cell death that depends on the autophagy genes.
Journal Article
Intracellular ATP levels determine cell death fate by apoptosis or necrosis
TL;DR: This study addressed the question of whether apoptosis depends on intracellular ATP levels, since longer incubation under ATP-depleting conditions results in necrotic cell death, and indicated that ATP levels are a determinant of manifestation of cell death.