J
Junsung Rho
Researcher at Harvard University
Publications - 11
Citations - 3970
Junsung Rho is an academic researcher from Harvard University. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 8, co-authored 11 publications receiving 3669 citations. Previous affiliations of Junsung Rho include Howard Hughes Medical Institute & Northwestern University.
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Facile Conjugation of Biomolecules onto Surfaces via Mussel Adhesive Protein Inspired Coatings
TL;DR: A facile two-step aqueous approach to immobilization of biomolecules onto surfaces is reported, which exploits the latent reactivity of the biomimetic polymer thin film towards nucleophiles, is unaffected by water, and allows for discrimination betweenucleophiles on the basis of pKa.
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Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts.
Akiko Doi,In-Hyun Park,Bo Wen,Peter Murakami,Martin J. Aryee,Rafael A. Irizarry,Brian R. Herb,Christine Ladd-Acosta,Junsung Rho,Sabine Loewer,Justine D. Miller,Thorsten M. Schlaeger,George Q. Daley,Andrew P. Feinberg +13 more
TL;DR: Substantial hypermethylation and hypomethylation of cytosine-phosphate-guanine island shores in nine human iPS cell lines as compared to their parental fibroblasts are found, suggesting two mechanisms for epigenetic reprogramming in iPS cells and cancer.
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Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells
Elayne M. Chan,Sutheera Ratanasirintrawoot,Sutheera Ratanasirintrawoot,In-Hyun Park,Philip D. Manos,Philip D. Manos,Yuin-Han Loh,Hongguang Huo,Hongguang Huo,Justine D. Miller,Justine D. Miller,Odelya Hartung,Odelya Hartung,Junsung Rho,Tan A. Ince,George Q. Daley,Thorsten M. Schlaeger,Thorsten M. Schlaeger +17 more
TL;DR: Using serial live imaging of human fibroblasts undergoing reprogramming to identify distinct colony types that morphologically resemble embryonic stem cells yet differ in molecular phenotype and differentiation potential, it is determined that only one colony type represents true iPS cells, whereas the others represent reprograming intermediates.
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Substrate-Independent Layer-by-Layer Assembly by Using Mussel-Adhesive-Inspired Polymers†
TL;DR: Layer-by-layer (LbL) assembly has attracted much attention because of its ability to create multifunctional films on surfaces while maintaining bulk properties and extensive control over film properties and composition during stepwise adsorption of components.
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Norepinephrine: material-independent, multifunctional surface modification reagent.
TL;DR: P pH-induced oxidative polymerization of norepinephrine forms adherent films on vastly different types of material surfaces of noble metals, metal oxides, semiconductors, ceramics, shape-memory alloys, and synthetic polymers.