J
Jyoti K. Jaiswal
Researcher at George Washington University
Publications - 90
Citations - 8294
Jyoti K. Jaiswal is an academic researcher from George Washington University. The author has contributed to research in topics: Myocyte & Muscular dystrophy. The author has an hindex of 35, co-authored 82 publications receiving 7435 citations. Previous affiliations of Jyoti K. Jaiswal include Children's National Medical Center & National Institutes of Health.
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Long-term multiple color imaging of live cells using quantum dot bioconjugates
TL;DR: Two approaches presented are endocytic uptake of QDs and selective labeling of cell surface proteins with QDs conjugated to antibodies, which should permit the simultaneous study of multiple cells over long periods of time as they proceed through growth and development.
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Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy.
TL;DR: This work used QDs and emission spectrum scanning multiphoton microscopy to develop a means to study extravasation in vivo and establishes the safety of QDs for in vivo studies, and permits the study of multicellular interactions in vivo.
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Synthesis of compact multidentate ligands to prepare stable hydrophilic quantum dot fluorophores.
TL;DR: These ligands provide a straightforward means of preparing QDs that exhibit greater resistance to environmental changes, making them more amenable for use in live cell imaging and other biotechnological applications.
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Potentials and pitfalls of fluorescent quantum dots for biological imaging
TL;DR: Although there have been many successes in using QDs for biological applications, limitations remain that must be overcome before these powerful tools can be used routinely by biologists.
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Membrane proximal lysosomes are the major vesicles responsible for calcium-dependent exocytosis in nonsecretory cells
TL;DR: Using total internal reflection fluorescence microscopy, it was observed that many organelles implicated in this process, including ER, post-Golgi vesicles, late endosome, early endosomes, and lysosomes were within 100 nm of the plasma membrane (in the evanescent field), however, an increase in cytosolic calcium led to exocytosis of only the l Lysosomes.