H
H. Tetsuo Uyeda
Researcher at United States Naval Research Laboratory
Publications - 22
Citations - 9885
H. Tetsuo Uyeda is an academic researcher from United States Naval Research Laboratory. The author has contributed to research in topics: Förster resonance energy transfer & Quantum dot. The author has an hindex of 16, co-authored 22 publications receiving 9500 citations. Previous affiliations of H. Tetsuo Uyeda include Massachusetts Institute of Technology & Dresden University of Technology.
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Journal ArticleDOI
Quantum dot bioconjugates for imaging, labelling and sensing
TL;DR: This review looks at current methods for preparing QD bioconjugates as well as presenting an overview of applications, and concludes that the potential of QDs in biology has just begun to be realized and new avenues will arise as the ability to manipulate these materials improves.
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Multiplexed toxin analysis using four colors of quantum dot fluororeagents.
Ellen R. Goldman,Aaron R. Clapp,George M. Anderson,H. Tetsuo Uyeda,J. Matthew Mauro,Igor L. Medintz,Hedi Mattoussi +6 more
TL;DR: This work prepared bioinorganic conjugates made with highly luminescent semiconductor nanocrystals and antibodies and antibodies to perform multiplexed fluoroimmunoassays and demonstrated the simultaneous detection of the four toxins from a single sample probed with a mixture of all four QD-antibody reagents.
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Synthesis of compact multidentate ligands to prepare stable hydrophilic quantum dot fluorophores.
TL;DR: These ligands provide a straightforward means of preparing QDs that exhibit greater resistance to environmental changes, making them more amenable for use in live cell imaging and other biotechnological applications.
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A Hybrid Quantum Dot−Antibody Fragment Fluorescence Resonance Energy Transfer-Based TNT Sensor
Ellen R. Goldman,Igor L. Medintz,Jessica L. Whitley,Andrew Hayhurst,Aaron R. Clapp,H. Tetsuo Uyeda,Jeffrey R. Deschamps,Michael E. Lassman,Hedi Mattoussi +8 more
TL;DR: The use of luminescent QDs conjugated to antibody fragments to develop solution-phase nanoscale sensing assemblies, based on fluorescence resonance energy transfer (FRET) for the specific detection of the explosive 2,4,6-trinitrotoluene (TNT) in aqueous environments is demonstrated.
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Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates.
Igor L. Medintz,Aaron R. Clapp,Florence M. Brunel,Theresa Tiefenbrunn,H. Tetsuo Uyeda,Eddie L. Chang,Jeffrey R. Deschamps,Philip E. Dawson,Hedi Mattoussi +8 more
TL;DR: Luminescent quantum dot bioconjugates designed to detect proteolytic activity by fluorescence resonance energy transfer are presented, not limited to sensing proteases, but may be amenable to monitoring other enzymatic modifications.