J
J. Matthew Mauro
Researcher at United States Naval Research Laboratory
Publications - 38
Citations - 9582
J. Matthew Mauro is an academic researcher from United States Naval Research Laboratory. The author has contributed to research in topics: Quantum dot & Biosensor. The author has an hindex of 22, co-authored 38 publications receiving 9316 citations. Previous affiliations of J. Matthew Mauro include Molecular Probes & United States Department of the Navy.
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Journal ArticleDOI
Long-term multiple color imaging of live cells using quantum dot bioconjugates
TL;DR: Two approaches presented are endocytic uptake of QDs and selective labeling of cell surface proteins with QDs conjugated to antibodies, which should permit the simultaneous study of multiple cells over long periods of time as they proceed through growth and development.
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Self-Assembly of CdSe−ZnS Quantum Dot Bioconjugates Using an Engineered Recombinant Protein
Hedi Mattoussi,J. Matthew Mauro,Ellen R. Goldman,George M. Anderson,Vikram C. Sundar,and Frederic V. Mikulec,Moungi G. Bawendi +6 more
TL;DR: A novel and direct method is described for conjugating protein molecules to luminescent CdSe−ZnS core−shell nanocrystals (Quantum Dots) for use as bioactive fluorescent probes in sensing, imaging, immunoassay, and other diagnostics applications.
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Self-assembled nanoscale biosensors based on quantum dot FRET donors
Igor L. Medintz,Aaron R. Clapp,Hedi Mattoussi,Ellen R. Goldman,Brent Fisher,J. Matthew Mauro,J. Matthew Mauro +6 more
TL;DR: The design, formation and testing of QD–protein assemblies that function as chemical sensors that overcomes inherent QD donor–acceptor distance limitations are reported.
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Fluorescence resonance energy transfer between quantum dot donors and dye-labeled protein acceptors.
Aaron R. Clapp,Igor L. Medintz,J. Matthew Mauro,Brent Fisher,Moungi G. Bawendi,Hedi Mattoussi +5 more
TL;DR: Results showed a clear dependence of the efficiency on the spectral overlap between the QD donor and dye acceptor and a good model system to explore FRET phenomena in QD-protein-dye conjugates.
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Multiplexed toxin analysis using four colors of quantum dot fluororeagents.
Ellen R. Goldman,Aaron R. Clapp,George M. Anderson,H. Tetsuo Uyeda,J. Matthew Mauro,Igor L. Medintz,Hedi Mattoussi +6 more
TL;DR: This work prepared bioinorganic conjugates made with highly luminescent semiconductor nanocrystals and antibodies and antibodies to perform multiplexed fluoroimmunoassays and demonstrated the simultaneous detection of the four toxins from a single sample probed with a mixture of all four QD-antibody reagents.