K
K. M. Muraleedharan
Researcher at Indian Institute of Technology Madras
Publications - 49
Citations - 802
K. M. Muraleedharan is an academic researcher from Indian Institute of Technology Madras. The author has contributed to research in topics: Artemisinin & Carboxylic acid. The author has an hindex of 12, co-authored 47 publications receiving 751 citations. Previous affiliations of K. M. Muraleedharan include University of Mississippi & Indian Institute of Chemical Technology.
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A modular approach towards drug delivery vehicles using oxanorbornane-based non-ionic amphiphiles
TL;DR: The self-assembly of non-ionic amphiphiles with a hydroxylated oxanorbornane head-group was controlled using amino acid units as spacers between hydrophilic and lipophilic domains to get spherical supramolecular aggregates, and the intervening amino acid unit was found to help in drug entrapment as well.
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Chemical environment as control element in the evolution of shapes – ‘hexagons and rods’ from an 11-helical α,β2,3-hybrid peptide
TL;DR: In this article, chemical environment-dependent supramolecular assembly of 11-helical α,β2,3-hybrid peptide which give hexagonal or rod-like microcrystalline structures is demonstrated.
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Regio-selective lipase catalyzed hydrolysis of oxanorbornane-based sugar-like amphiphiles at air-water interface: A polarized FT-IRRAS study.
TL;DR: Interfacial hydrolysis of oxanorbornane-based amphiphile (Triol C16) by Candida rugosa lipase was investigated using real-time polarized Fourier transform-infrared reflection absorption spectroscopy (FT-IRRAS) to demonstrate further the potential of IRRAS spectroscopic monitoring the hydrolytic product formation and selectivity at biomimetic interfaces.
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trans-β2,3-Amino Acid-Based Supramolecular Synthons for Probing the Interrelationships between Structure, Torsion-Directed Assembly, and Isomorphism
TL;DR: In this article, a group of trans-β2,3 amino acid derivatives with Boc and oxazolidinone moieties at the N- and C-terminals are discussed.
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As Many as Six Tandem Reactions in One Step! Unprecedented Formation of Highly Functionalized Benzothiophenes.
Pushparathinam Gopinath,Surapaneni Nilaya,Tripathy Ranjan Debi,Venkatachalam Ramkumar,K. M. Muraleedharan +4 more
TL;DR: In this article, a reaction pathway involving 1,3-diketones and 2,2′-dithiodibenzoylchloride that gives access to benzothiophenes with spiroketal, lactone, carbonyl, hydroxyl and carboxylic acid functionalities is discussed.