K
K. Srinivasan
Researcher at Indian Veterinary Research Institute
Publications - 24
Citations - 3262
K. Srinivasan is an academic researcher from Indian Veterinary Research Institute. The author has contributed to research in topics: Unfolded protein response & Insulin resistance. The author has an hindex of 18, co-authored 24 publications receiving 2927 citations.
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Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening.
TL;DR: The present study represents that the combination of HFD-fed and low-dose STZ-treated rat serves as an alternative animal model for type 2 diabetes simulating the human syndrome that is also suitable for testing anti-diabetic agents for the treatment of type 1 diabetes.
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Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats
TL;DR: It is demonstrated that mangiferin possesses significant antidiabetic, antihyperlipidemic and antiatherogenic properties thus suggesting its beneficial effect in the treatment of diabetes mellitus associated with hyperlipidemia and related cardiovascular complications.
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Reversal of glucose intolerance by by pioglitazone in high fat diet-fed rats.
TL;DR: It is demonstrated that the adult male rats on a HFD for 4 weeks exhibited the characteristic features of obesity, insulin resistance and glucose intolerance, namely increased body weight, increased total fat pad weight, mild basal/fasting hyperglycemia, hyperinsulinemia, hypertriglyceridemia, hypercholesterolemia and impaired oral glucose tolerance.
Journal ArticleDOI
Evaluation of anti-inflammatory activity of Pongamia pinnata leaves in rats.
K. Srinivasan,Shanmugam Muruganandan,J Lal,Sadanandavalli Retnaswami Chandra,Surendra K. Tandan,V. Ravi Prakash +5 more
TL;DR: It is indicated that PLE possesses significant anti-inflammatory activity without ulcerogenic activity suggesting its potential as an anti- inflammation agent for use in the treatment of various inflammatory diseases.
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Anti-inflammatory activity of Syzygium cumini bark.
Shanmugam Muruganandan,K. Srinivasan,Sadanandavalli Retnaswami Chandra,Surendra K. Tandan,J Lal,V. Raviprakash +5 more
TL;DR: It is demonstrated that S. cumini bark extract has a potent anti-inflammatory action against different phases of inflammation without any side effect on gastric mucosa.