K
Kai Hou
Publications - 3
Citations - 151
Kai Hou is an academic researcher. The author has contributed to research in topics: Cell & Endoplasmic reticulum. The author has an hindex of 3, co-authored 3 publications receiving 141 citations.
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Journal ArticleDOI
Rapamycin Upregulates Autophagy by Inhibiting the mTOR-ULK1 Pathway, Resulting in Reduced Podocyte Injury
Lingling Wu,Zhe Feng,Shaoyuan Cui,Kai Hou,Li Tang,Jianhui Zhou,Guangyan Cai,Yuansheng Xie,Quan Hong,Bo Fu,Xiangmei Chen +10 more
TL;DR: In vivo and in vitro experiments demonstrate that podocyte injury is associated with changes in autophagy levels, and that rapamycin can reduce podocytes injury by increasing autophagic levels via inhibition of the mTOR-ULK1 pathway.
Journal ArticleDOI
Knockdown of fibronectin induces mitochondria-dependent apoptosis in rat mesangial cells.
Di Wu,Xiangmei Chen,Deng-Fu Guo,Quan Hong,Bo Fu,Rui Ding,Lifang Yu,Kai Hou,Zhe Feng,Xiaojie Zhang,Jianzhong Wang +10 more
TL;DR: Two studies explored a new method for simultaneously inhibiting MC proliferation and ECM accumulation, which may represent a novel therapeutic approach to glomerulosclerosis.
Journal ArticleDOI
Membrane topology structure of human high-affinity, sodium-dependent dicarboxylate transporter
TL;DR: Results support the topography of 11 transmembrane domains with an extracellular C terminus and an intracellular N terminus of Na DC3, and for the first time provide experimental evidence for a novel topological model for NaDC3.