The American Society for Testing and Materials (ASTM) is an independent organization devoted to the development of standards.

American Society for Testing and Materials

羟氨苄青霉素引起大疱性类天疱疮样疹

The present report is submitted in response to General Assembly resolution 61/106, by which the Assembly adopted the Convention on the Rights of Persons with Disabilities and the Optional Protocol thereto. As requested by the Assembly, a brief overview of the status of the Convention as at 3 August 2007 is presented. The report also contains a brief description of technical arrangements on staff and facilities made necessary for the effective performance of the functions of the Conference of States Parties and the Committee under the Convention and the Optional Protocol, and a description on the progressive implementation of standards and guidelines for the accessibility of facilities and services of the United Nations system. Recent efforts of the United Nations and agencies to disseminate information on the Convention and the Optional Protocol are also described.

わかりやすい障害者の権利条約 : 知的障害のある人の権利のために = Convention on the rights of persons with disabilities

Oxidative stress is a normal phenomenon in the body. Under normal conditions, the physiologically important intracellular levels of reactive oxygen species (ROS) are maintained at low levels by various enzyme systems participating in the in vivo redox homeostasis. Therefore, oxidative stress can also be viewed as an imbalance between the prooxidants and antioxidants in the body. For the last two decades, oxidative stress has been one of the most burning topics among the biological researchers all over the world. Several reasons can be assigned to justify its importance: knowledge about reactive oxygen and nitrogen species production and metabolism; identification of biomarkers for oxidative damage; evidence relating manifestation of chronic and some acute health problems to oxidative stress; identification of various dietary antioxidants present in plant foods as bioactive molecules; and so on. This review discusses the importance of oxidative stress in the body growth and development as well as proteomic and genomic evidences of its relationship with disease development, incidence of malignancies and autoimmune disorders, increased susceptibility to bacterial, viral, and parasitic diseases, and an interplay with prooxidants and antioxidants for maintaining a sound health, which would be helpful in enhancing the knowledge of any biochemist, pathophysiologist, or medical personnel regarding this important issue.

/pdf/oxidative-stress-prooxidants-and-antioxidants-the-interplay-4xs72vw50w.pdf

Oxidative Stress, Prooxidants, and Antioxidants: The Interplay

European Resuscitation Council Guidelines for Resuscitation 2015

It is accepted that the earth's climate is changing in an accelerating pace, with already documented implications for human health and the environment. This literature review provides an overview of existing research findings about the effects of heat stress on the working population in relation to climate change. In the light of climate change adaptation, the purpose of the literature review was to explore recent and previous research into the impacts of heat stress on humans in an occupational setting. Heat stress in the workplace has been researched extensively in the past however, in the contemporary context of climate change, information is lacking on its extent and implications. The main factors found to exacerbate heat stress in the current and future workplace are the urban 'heat island effect', physical work, individual differences, and the developing country context where technological fixes are often not applicable. There is also a lack of information on the effects on vulnerable groups such as elderly people and pregnant women. As increasing tempera- tures reduce work productivity, world economic productivity could be condensed, affecting devel- oping countries in the tropical climate zone disproportionately. Future research is needed taking an interdisciplinary approach, including social, economic, environmental and technical aspects.

/pdf/effects-of-heat-stress-on-working-populations-when-facing-5ef3200r7s.pdf

Effects of Heat Stress on Working Populations when Facing Climate Change

Investigating claims that a clothed person's mass loss does not always represent their evaporative heat loss (EVAP), a thermal manikin study was performed measuring heat balance components in more ...

https://www.physiology.org/doi/pdf/10.1152/japplphysiol.00612.2007

Apparent latent heat of evaporation from clothing: attenuation and “heat pipe” effects

in Undetermined The impact of heat waves arising from climate change on human health is predicted to be profound. It is important to be prepared with various preventive measures for such impacts on society. The objective of this study was to investigate whether personal cooling with phase change materials (PCM) could improve thermal comfort in simulated office work at 34°C. Cooling vests with PCM were measured on a thermal manikin before studies on human subjects. Eight male subjects participated in the study in a climatic chamber (T(a) = 34°C, RH = 60%, and ν(a) = 0.4 m/s). Results showed that the cooling effect on the manikin torso was 29.1 W/m(2) in the isothermal condition. The results on the manikin using a constant heating power mode reflect directly the local cooling effect on subjects. The results on the subjects showed that the torso skin temperature decreased by about 2-3°C and remained at 33.3°C. Both whole body and torso thermal sensations were improved. The findings indicate that the personal cooling with PCM can be used as an option to improve thermal comfort for office workers without air conditioning and may be used for vulnerable groups, such as elderly people, when confronted with heat waves. PRACTICAL IMPLICATIONS: Wearable personal cooling integrated with phase change materials has the advantage of cooling human body's micro-environment in contrast to stationary personalized cooling and entire room or building cooling, thus providing greater mobility and helping to save energy. In places where air conditioning is not usually used, this personal cooling method can be used as a preventive measure when confronted with heat waves for office workers, vulnerable populations such as the elderly and disabled people, people with chronic diseases, and for use at home. (Less)

Personal cooling with phase change materials to improve thermal comfort from a heat wave perspective

A previous study by the authors using a heated thermal manikin showed that the cooling rates of phase change material (PCM) are dependent on temperature gradient, mass, and covering area. The objective of this study was to investigate if the cooling effects of the temperature gradient observed on a thermal manikin could be validated on human subjects in extreme heat. The subjects wore cooling vests with PCMs at two melting temperatures (24 and 28°C) and fire-fighting clothing and equipment, thus forming three test groups (vest24, vest28 and control group without the vest). They walked on a treadmill at a speed of 5 km/h in a climatic chamber (air temperature = 55°C, relative humidity = 30%, vapour pressure = 4,725 Pa, and air velocity = 0.4 m/s). The results showed that the PCM vest with a lower melting temperature (24°C) has a stronger cooling effect on the torso and mean skin temperatures than that with a higher melting temperature (28°C). Both PCM vests mitigate peak core temperature increase during the resting recovery period. The two PCM vests tested, however, had no significant effect on the alleviation of core temperature increase during exercise in the heat. To study the possibility of effective cooling of core temperature, cooling garments with PCMs at even lower melting temperatures (e.g. 15°C) and a larger covering area should be investigated.

Cooling vests with phase change materials: the effects of melting temperature on heat strain alleviation in an extremely hot environment

Phase change material (PCM) absorbs or releases latent heat when it changes phases, making thermal-regulated clothing possible. The objective of this study was to quantify the relationships between PCM cooling rate and temperature gradient, mass, and covering area on a thermal manikin in a climatic chamber. Three melting temperatures (24, 28, 32 °C) of the PCMs, different mass, covering areas, and two manikin temperatures (34 and 38 °C) were used. The results showed that the cooling rate of the PCM vests tested is positively correlated with the temperature gradient between the thermal manikin and the melting temperature of the PCMs. The required temperature gradient is suggested to be greater than 6 °C when PCM vests are used in hot climates. With the same temperature gradient, the cooling rate is mainly determined by the covering area. The duration of the cooling effect is dependent on PCM mass and the latent heat

Kalev Kuklane

Papers

Effects of Heat Stress on Working Populations when Facing Climate Change

Apparent latent heat of evaporation from clothing: attenuation and “heat pipe” effects

Personal cooling with phase change materials to improve thermal comfort from a heat wave perspective

Cooling vests with phase change materials: the effects of melting temperature on heat strain alleviation in an extremely hot environment

Cooling vests with phase change material packs: the effects of temperature gradient, mass and covering area.