K
Kalpana Agarwal
Researcher at University of Calcutta
Publications - 14
Citations - 365
Kalpana Agarwal is an academic researcher from University of Calcutta. The author has contributed to research in topics: In vivo & Genotoxicity. The author has an hindex of 9, co-authored 14 publications receiving 355 citations.
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Journal ArticleDOI
Clastogenic effect of fenfluramine in mice bone marrow cells in vivo
Kalpana Agarwal,Anita Mukherjee,Archana Sharma,Ramesh C. Sharma,Kuldip Raj Bhardwaj,Soumitra Sen +5 more
TL;DR: Fenfluramine is moderately clastogenic and a DNA damaging agent in vivo, indicating that the maximum effect occurs at the middle or late synthetic phase of the cell cycle.
Journal ArticleDOI
Genotoxicity studies of the food additive ester gum
TL;DR: Although EG was weakly clastogenic and could induce a marginal increase in sister chromatid exchange frequencies, it was not a potential health hazard at the doses tested.
Journal ArticleDOI
Potentiation by caffeine of the frequencies of chromosomal aberrations induced by chronic exposure to fenfluramine in mice.
TL;DR: The hypothesis that prolonged Fen application induces dose-dependent increase in post-replication repair and caffeine enhanced toxicity by inhibiting repair process(es) is supported and the study suggests that Fen is a clastogen and since caffeine may have a synergistic effect, it should be avoided during treatment.