Kalthoum Tizaoui

TL;DR: The aim of this study was to quantify the magnitude of the risk associated with the TaqI, BsmI, ApaI and FokI VDR polymorphisms in MS using a meta-analysis approach.

TL;DR: Results indicate that ABCB1 C3435T polymorphism, especially TT genotype, plays an important role in refractory epilepsy and genetic screening of this genotype may be useful to predict AEDs response before starting the treatment, as further investigations should validate the association.

TL;DR: Stratification according to study characteristics showed that publication year, age, gender, estimated vitamin D levels and latitude moderated significantly association between VDR polymorphisms and T1D disease.

TL;DR: The current understanding of the immunopathogenesis of ANCA-associated vasculitis and the interplay between ANCA serotype and proposed disease biomarkers are summarized and it is illustrated how the extending knowledge of the Immunopathogenesis will likely translate into development of a personalized medicine approach in the management of AN CA-associated Vasculitis.

TL;DR: It is suggested that IL-17F 7488G allele is associated with increased lung cancer risk in the Tunisian population, and the existence of a biological interaction between IL- 17A, but not IL-16F polymorphisms and smoking is suggested.