K
Kamelia M. Amin
Researcher at Cairo University
Publications - 47
Citations - 1056
Kamelia M. Amin is an academic researcher from Cairo University. The author has contributed to research in topics: Indole test & Benzofuran. The author has an hindex of 16, co-authored 45 publications receiving 916 citations. Previous affiliations of Kamelia M. Amin include Helwan University & Al-Azhar University.
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Synthesis and preliminary evaluation of some substituted coumarins as anticonvulsant agents.
TL;DR: No clear correlation was observed between the antiepileptic activity and molecular lipophilicity descriptors of the tested compounds, and some selected compounds were assayed against seizures induced by pentylenetetrazole and strychnine in mice.
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Synthesis, anticoagulant and PIVKA-II induced by new 4-hydroxycoumarin derivatives
Omaima M. Abdelhafez,Kamelia M. Amin,Rasha Z. Batran,Timothy J. Maher,Somaia A. Nada,Shalini Sethumadhavan +5 more
TL;DR: A comparative in vivo and in vitro study with respect to warfarin showed that the synthesized compounds have different anticoagulant activities, the most prospective compounds were the 3-pyrazolyl-4-hydroxycoumarin derivatives.
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Synthesis, biological evaluation and molecular docking of novel series of spiro [(2H,3H) quinazoline-2,1'- cyclohexan]-4(1H)- one derivatives as anti-inflammatory and analgesic agents.
TL;DR: Three series of Spiro [(2H,3H) quinazoline-2,1'-cyclohexan]-4(1H)-one derivatives have been synthesized and showed considerable potent anti-inflammatory and analgesic activity and safety profile in experimental rats in comparing to indomethacin and tramadol as reference drugs.
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New quinoxaline 1,4-di-N-oxides. Part 1: Hypoxia-selective cytotoxins and anticancer agents derived from quinoxaline 1,4-di-N-oxides
TL;DR: A new series of quinoxaline 1,4-di-N-oxides and fused quin Oxides were synthesized and evaluated for hypoxic-cytotoxic activity on EAC cell line and Tirapazamine has been shown to be an efficient and selective cytotoxin after bioreductive activation in hypoxic cells.
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New quinoxaline 1, 4-di-N-oxides: anticancer and hypoxia-selective therapeutic agents
TL;DR: A new series of quinoxaline 1,4-di-N-oxides was synthesized and evaluated for antitumor and hypoxic-selective cytotoxic activities and compound 4 was the most potent hypoxia selective-cytotoxin on EAC cell line.