Kamil Novak

TL;DR: The structure and mechanical properties of adventitia are well designed to protect the media from axial and circumferential overloads, which explains the origin of wall anisotropy seen at this strain level.

TL;DR: The data demonstrated that the biomechanical rupture risk assessment is superior to maximal diameter in predicting AAA rupture up to 9 months ahead and significantly decreases the false-positive rate.

TL;DR: A new automated method for evaluation of collagen fiber direction from two-dimensional polarized light microscopy images (2D PLM) has been proposed and has the potential to replace manual measurements of collagen orientation via PLM.

TL;DR: Investigating their correlations with alternative rupture risk indicators as peak wall stress (PWS) and peak wall rupture risk (PWRR) to decide which Dmax is more relevant in AAA rupture risk assessment confirmed that orthoDmax is better correlated with theAlternative rupture risk predictors PWS and PWRR for angulated AAAs while there is no difference between ortho Dmax and axialDmax for straight AAAs.

TL;DR: It was shown that for majority of AAAs the differences are insignificant but for some 10% of them their relative differences exceed 20% which may lead to incorrect decisions on their surgical treatment, which favours application of realistic material models in clinical practise although they are much more time-consuming.