K
Kan Zen
Researcher at Kyoto Prefectural University of Medicine
Publications - 118
Citations - 1795
Kan Zen is an academic researcher from Kyoto Prefectural University of Medicine. The author has contributed to research in topics: Medicine & Stent. The author has an hindex of 18, co-authored 99 publications receiving 1465 citations. Previous affiliations of Kan Zen include Community Medical Center & Kyoto Prefectural University.
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Journal ArticleDOI
Very low frequency power of heart rate variability is a powerful predictor of clinical prognosis in patients with congestive heart failure.
Mitsuyoshi Hadase,Akihiro Azuma,Kan Zen,Satoshi Asada,Tatsuya Kawasaki,Tadaaki Kamitani,Shingo Kawasaki,Hiroki Sugihara,Hiroaki Matsubara +8 more
TL;DR: VLF power is an independent risk predictor in patients with CHF and predicted cardiac events independently of LF power, TP, DM, BNP and NYHA functional class in multivariate analysis.
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Endovascular Treatment for Infrainguinal Vessels in Patients With Critical Limb Ischemia OLIVE Registry, a Prospective, Multicenter Study in Japan With 12-Month Follow-up
Osamu Iida,Masato Nakamura,Yasutaka Yamauchi,Daizo Kawasaki,Yoshiaki Yokoi,Hiroyoshi Yokoi,Y. Soga,Kan Zen,Keisuke Hirano,Nobuhiro Suematsu,Naoto Inoue,Kenji Suzuki,Yoshiaki Shintani,Yusuke Miyashita,Kazushi Urasawa,Ikuro Kitano,Terutoshi Yamaoka,Takashi Murakami,Michitaka Uesugi,Taketsugu Tsuchiya,Toshiro Shinke,Yasuhiro Oba,Norihiko Ohura,Toshimitsu Hamasaki,Shinsuke Nanto +24 more
TL;DR: In this article, a prospective multicenter study was conducted to evaluate the clinical outcomes of Japanese critical limb ischemia patients (mean age, 73±10 years) with infrainguinal arterial lesions who underwent EVT.
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1-Year Results of the ZEPHYR Registry (Zilver PTX for the Femoral Artery and Proximal Popliteal Artery): Predictors of Restenosis
Osamu Iida,Mitsuyoshi Takahara,Yoshimitsu Soga,Masatsugu Nakano,Yasutaka Yamauchi,Kan Zen,Daizo Kawasaki,Shinsuke Nanto,Hiroyoshi Yokoi,Masaaki Uematsu,Zephyr Investigators +10 more
TL;DR: 1-year real-world outcomes after drug-eluting stent treatment for FP lesions, including challenging ones in clinical practice were demonstrated, with lesion length, external elastic membrane area, and minimum stent area being independent predictors for restenosis.
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Pressure-Mediated Hypertrophy and Mechanical Stretch Induces IL-1 Release and Subsequent IGF-1 Generation to Maintain Compensative Hypertrophy by Affecting Akt and JNK Pathways
Shoken Honsho,Susumu Nishikawa,Katsuya Amano,Kan Zen,Yasushi Adachi,Eigo Kishita,Akihiro Matsui,Asako Katsume,Shinichiro Yamaguchi,Kenichiro Nishikawa,Kikuo Isoda,David W. H. Riches,Satoaki Matoba,Mitsuhiko Okigaki,Hiroaki Matsubara +14 more
TL;DR: It is demonstrated for the first time that pressure-mediated hypertrophy and mechanical stretch generates a subinflammatory low level of IL-1&bgr;, which constitutively causes IGF-1 production to maintain adaptable compensation hypertropy and inhibit interstitial fibrosis.
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Cilostazol Reduces Angiographic Restenosis After Endovascular Therapy for Femoropopliteal Lesions in the Sufficient Treatment of Peripheral Intervention by Cilostazol Study
Osamu Iida,Hiroyoshi Yokoi,Yoshimitsu Soga,Naoto Inoue,Kenji Suzuki,Yoshiaki Yokoi,Daizo Kawasaki,Kan Zen,Kazushi Urasawa,Yoshiaki Shintani,Akira Miyamoto,Keisuke Hirano,Yusuke Miyashita,Taketsugu Tsuchiya,Norihiko Shinozaki,Masato Nakamura,Takaaki Isshiki,Toshimitsu Hamasaki,Shinsuke Nanto +18 more
TL;DR: Cilostazol reduced angiographic restenosis after percutaneous transluminal angioplasty with provisional nitinol stenting for femoropopliteal lesions and had a significantly higher event-free survival at 12 months.