K
Kapil Suchal
Researcher at All India Institute of Medical Sciences
Publications - 23
Citations - 925
Kapil Suchal is an academic researcher from All India Institute of Medical Sciences. The author has contributed to research in topics: Oxidative stress & Nephrotoxicity. The author has an hindex of 14, co-authored 20 publications receiving 613 citations.
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Journal ArticleDOI
Apigenin ameliorates streptozotocin-induced diabetic nephropathy in rats via MAPK/NF-κB/TNF-α and TGF-β1/MAPK/Fibronectin pathways
Salma Malik,Kapil Suchal,Sana Irfan Khan,Jagriti Bhatia,Kamal Kishore,Amit K. Dinda,Dharamvir Singh Arya +6 more
TL;DR: Apigenin ameliorated renal damage due to DN by suppressing oxidative stress and fibrosis and by inhibiting MAPK pathway, which significantly prevented MAPK activation.
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Telmisartan ameliorates cisplatin-induced nephrotoxicity by inhibiting MAPK mediated inflammation and apoptosis
TL;DR: Investigating the protective effect of telmisartan in cisplatin-induced nephrotoxicity model in rats showed maximum nephroprotective effect which could be due to maintenance of cellular redox status and inhibition of MAPK activation.
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Pharmacological Properties, Molecular Mechanisms, and Pharmaceutical Development of Asiatic Acid: A Pentacyclic Triterpenoid of Therapeutic Promise.
Mohamed Fizur Nagoor Meeran,Sameer N. Goyal,Kapil Suchal,Charu Sharma,Chandragouda R. Patil,Shreesh Ojha +5 more
TL;DR: Provided the favorable pharmacokinetics, safety, and efficacy, AA can be a promising agent or adjuvant along with currently used modern medicines with a pharmacological basis of its use in therapeutics.
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Kaempferol Attenuates Myocardial Ischemic Injury via Inhibition of MAPK Signaling Pathway in Experimental Model of Myocardial Ischemia-Reperfusion Injury
Kapil Suchal,Salma Malik,Nanda Gamad,Rajiv Kumar Malhotra,Sameer N. Goyal,Uma Chaudhary,Jagriti Bhatia,Shreesh Ojha,Dharamvir Singh Arya +8 more
TL;DR: KMP protected against IR injury by attenuating inflammation and apoptosis through the modulation of MAPK pathway by maintaining cardiac function, normalizing oxidative stress, and preserving morphological alterations.
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Molecular Pathways Involved in the Amelioration of Myocardial Injury in Diabetic Rats by Kaempferol
Kapil Suchal,Salma Malik,Sana Irfan Khan,Rajiv Kumar Malhotra,Sameer N. Goyal,Jagriti Bhatia,Shreesh Ojha,Dharamvir Singh Arya +7 more
TL;DR: Kaempferol attenuated myocardial ischemia-reperfusion injury in diabetic rats by reducing AGE-RAGE/ mitogen activated protein kinase (MAPK) induced oxidative stress and inflammation.