K
Karen E. Asin
Researcher at University of Illinois at Chicago
Publications - 55
Citations - 1830
Karen E. Asin is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Agonist & Dopamine receptor D1. The author has an hindex of 27, co-authored 55 publications receiving 1783 citations.
Papers
More filters
Journal ArticleDOI
Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats.
TL;DR: Long-term infusion of glucose, beta-hydroxybutyrate, and glycerol into the third ventricle of the rat brain caused a stabilization of body weight at a lower than normal level, consistent with the view that the systems controlling food intake and body weight are sensitive to the availability of brain fuels.
Journal ArticleDOI
Dopamine agonists and stress produce different patterns of Fos-like immunoreactivity in the lateral habenula
TL;DR: In rats treated systemically with either amphetamine, amfonelic acid or apomorphine, large numbers of cells displaying Fos-like immunoreactivity (FLI) could be seen in the lateral zone of the lateral habenula, and these findings support the concept of a functional differentiation of the medial and lateral regions of theateral habenulas.
Journal ArticleDOI
A68930: a potent agonist selective for the dopamine D1 receptor.
Michael P. DeNinno,Robert Schoenleber,Robert G. MacKenzie,Donald R. Britton,Karen E. Asin,Clark Briggs,Joel M. Trugman,Martha Ackerman,Linda D. Artman,Lisa Bednarz,Ramesh Bhatt,Peter Curzon,Edwin Gomez,Chae Hee Kang,James Stittsworth,John W. Kebabian +15 more
TL;DR: A68930, (1R,3S)-1-aminomethyl-5,6-dihydroxy-3-phenylisochroman HCl, is a potent (EC50 = 2.5 nM), partial (intrinsic activity = 66% of dopamine) agonist in the fish retina dopamine-sensitive adenylate cyclase model of the D1 dopamine receptor.
Journal ArticleDOI
Failure to establish a conditioned place preference with ethanol in rats.
TL;DR: The results may suggest that rats do not self-administer ethanol for its intoxicating properties, and that the affective state produced by ethanol administration per se is not readily conditionable to environmental cues.
Journal ArticleDOI
Evidence that electrolytic median raphe lesions increase locomotion but not exploration.
David Wirtshafter,Karen E. Asin +1 more
TL;DR: Electrolytic lesions of the median raphe nucleus were found to increase locomotion but decrease rearing in the open field, and these lesions eliminated the preference for entering a novel arm displayed by sham operated animals in a test of exploratory behavior.