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Karen E. Asin

Researcher at University of Illinois at Chicago

Publications -  55
Citations -  1830

Karen E. Asin is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Agonist & Dopamine receptor D1. The author has an hindex of 27, co-authored 55 publications receiving 1783 citations.

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Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats.

TL;DR: Long-term infusion of glucose, beta-hydroxybutyrate, and glycerol into the third ventricle of the rat brain caused a stabilization of body weight at a lower than normal level, consistent with the view that the systems controlling food intake and body weight are sensitive to the availability of brain fuels.
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Dopamine agonists and stress produce different patterns of Fos-like immunoreactivity in the lateral habenula

TL;DR: In rats treated systemically with either amphetamine, amfonelic acid or apomorphine, large numbers of cells displaying Fos-like immunoreactivity (FLI) could be seen in the lateral zone of the lateral habenula, and these findings support the concept of a functional differentiation of the medial and lateral regions of theateral habenulas.
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A68930: a potent agonist selective for the dopamine D1 receptor.

TL;DR: A68930, (1R,3S)-1-aminomethyl-5,6-dihydroxy-3-phenylisochroman HCl, is a potent (EC50 = 2.5 nM), partial (intrinsic activity = 66% of dopamine) agonist in the fish retina dopamine-sensitive adenylate cyclase model of the D1 dopamine receptor.
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Failure to establish a conditioned place preference with ethanol in rats.

TL;DR: The results may suggest that rats do not self-administer ethanol for its intoxicating properties, and that the affective state produced by ethanol administration per se is not readily conditionable to environmental cues.
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Evidence that electrolytic median raphe lesions increase locomotion but not exploration.

TL;DR: Electrolytic lesions of the median raphe nucleus were found to increase locomotion but decrease rearing in the open field, and these lesions eliminated the preference for entering a novel arm displayed by sham operated animals in a test of exploratory behavior.