Karin Zedeler

TL;DR: Multivariate analysis demonstrated that irradiation after mastectomy significantly improved disease-free survival and overall survival, irrespective of tumor size, the number of positive nodes, or the histopathological grade.

TL;DR: In this article, the axillary nodal status at the primary operation for breast cancer was evaluated in 13,851 patients registered by the Danish Breast Cancer Cooperative Group (DBCG).

TL;DR: The Nottingham Prognostic Index defined a subset of patients having so good prognosis that adjuvant therapy can be withhold, but it did not succeed in defining a subset with survival similar to the expected; additional prognostic factors are therefore needed.

TL;DR: The study suggests that all sources of delays should be kept at a minimum and indicates that doctors are capable of distinguishing between more and less aggressive malignancies.

TL;DR: Overall survival is significantly different in 82-b patients but not in post-menopausal 82-c patients, and adjuvant systemic treatment alone (chemotherapy or tamoxifen) did not prevent loco-regional recurrences in high-risk patients after mastectomy and axillary lymph node sampling.