K
Karola Prior
Researcher at University of Münster
Publications - 34
Citations - 2556
Karola Prior is an academic researcher from University of Münster. The author has contributed to research in topics: Multilocus sequence typing & Typing. The author has an hindex of 20, co-authored 31 publications receiving 2134 citations.
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Journal ArticleDOI
Prospective Genomic Characterization of the German Enterohemorrhagic Escherichia coli O104:H4 Outbreak by Rapid Next Generation Sequencing Technology
Alexander Mellmann,Dag Harmsen,Craig Cummings,Emily B. Zentz,Shana R. Leopold,Alain Rico,Karola Prior,Rafael Szczepanowski,Yongmei Ji,Wenlan Zhang,Stephen F. McLaughlin,John K. Henkhaus,Benjamin Leopold,Martina Bielaszewska,Rita Prager,Pius Brzoska,Richard Moore,Simone Guenther,Jonathan M. Rothberg,Helge Karch +19 more
TL;DR: It is suggested that by stepwise gain and loss of chromosomal and plasmid-encoded virulence factors, a highly pathogenic hybrid of EAEC and EHEC emerged as the current outbreak clone.
Journal ArticleDOI
Updating benchtop sequencing performance comparison
Sebastian Jünemann,Sebastian Jünemann,Fritz J. Sedlazeck,Karola Prior,Andreas Albersmeier,Uwe John,Jörn Kalinowski,Alexander Mellmann,Alexander Goesmann,Arndt von Haeseler,Jens Stoye,Dag Harmsen +11 more
TL;DR: An up-to-date snapshot of how benchtop platforms have evolved since the previous study is provided to bring readers’ attention to some shortcomings in the report from Loman et al.1.
Journal ArticleDOI
Defining and Evaluating a Core Genome Multilocus Sequence Typing Scheme for Whole-Genome Sequence-Based Typing of Listeria monocytogenes
Werner Ruppitsch,Ariane Pietzka,Karola Prior,Stefan Bletz,Haizpea Lasa Fernandez,Franz Allerberger,Dag Harmsen,Alexander Mellmann +7 more
TL;DR: A new L. monocytogenes typing scheme based on genome-wide gene-by-gene comparisons to allow for a unique typing nomenclature that improves outbreak investigations and enables interlaboratory exchange of data that are crucial, especially for rapid responses during transsectorial outbreaks.
Journal ArticleDOI
Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infection Control in an Institutional Setting
Alexander Mellmann,Stefan Bletz,Thomas Böking,Frank Kipp,Karsten Becker,Anja Schultes,Karola Prior,Dag Harmsen +7 more
TL;DR: Real-time microbial WGS in this institution was feasible, produced precise actionable results, helped us to monitor transmission rates that remained low following a modification in isolation procedures, and ultimately saved costs.
Journal ArticleDOI
Bacterial community shift in treated periodontitis patients revealed by ion torrent 16S rRNA gene amplicon sequencing.
Sebastian Jünemann,Sebastian Jünemann,Karola Prior,Rafael Szczepanowski,Inga Harks,Benjamin Ehmke,Alexander Goesmann,Jens Stoye,Dag Harmsen +8 more
TL;DR: Taxonomic analysis revealed different microbial shifts between both therapy approaches at all taxonomic levels, most remarkably, the genera Porphyromonas, Tannerella, Treponema, and Filifactor all harboring periodontal pathogenic species were removed almost only in the group treated with SPR and antibiotics.