K
Kassem Hamze
Researcher at Lebanese University
Publications - 18
Citations - 224
Kassem Hamze is an academic researcher from Lebanese University. The author has contributed to research in topics: Bacillus subtilis & Biology. The author has an hindex of 6, co-authored 13 publications receiving 195 citations. Previous affiliations of Kassem Hamze include University of Paris-Sud.
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Journal ArticleDOI
In situ localisation and quantification of surfactins in a Bacillus subtilis swarming community by imaging mass spectrometry
Delphine Debois,Kassem Hamze,Vincent Guérineau,Jean-Pierre Le Caer,I. Barry Holland,Philippe Lopes,Jamal Ouazzani,Simone J. Séror,Alain Brunelle,Olivier Laprévote +9 more
TL;DR: Surfactins were mainly located in the central mother colony (the site of initial inoculation), in a ‘ring’ surrounding the pattern and along the edges of the dendrites, whereas in the ring surrounding the swarm community and between dendrite, surfactins with longer fatty acyl chain lengths were found.
Journal ArticleDOI
Identification of genes required for different stages of dendritic swarming in Bacillus subtilis, with a novel role for phrC.
Kassem Hamze,Daria Julkowska,Sabine Autret,Krzysztof Hinc,Krzysztofa Nagorska,Agnieszka Sekowska,I. Barry Holland,Simone J. Séror +7 more
TL;DR: It is established that distinct early stages of dendritic swarming can be clearly defined, and that they are amenable to genetic analysis, which indicates a specific migration defect in the phrC mutant that could not be trans-complemented by CSF in a mixed swarm.
Journal ArticleDOI
Single-cell analysis in situ in a Bacillus subtilis swarming community identifies distinct spatially separated subpopulations differentially expressing hag (flagellin), including specialized swarmers.
Kassem Hamze,Sabine Autret,Krzysztof Hinc,Krzysztof Hinc,Soumaya Laalami,Daria Julkowska,Romain Briandet,Margareth Renault,Cédric Absalon,I. Barry Holland,Harald Putzer,Simone J. Séror +11 more
TL;DR: A model for this swarming process is discussed, emphasizing the importance of population density and of the complementary roles of packs of swarmers driving dendrite extension, while non-mobile cells in the stems extend dendrites by multiplication.
Journal ArticleDOI
The GTPase, CpgA(YloQ), a putative translation factor, is implicated in morphogenesis in Bacillus subtilis
Lionel Cladière,Kassem Hamze,Edwige Madec,Vladimir M. Levdikov,Anthony J. Wilkinson,I. Barry Holland,Simone J. Séror +6 more
TL;DR: The crystal structure of CPGA(YloQ) suggests a role as a translation initiation factor and the possibility that CpgA is involved in the translation of a subset of proteins, including some required for shape maintenance, is discussed.
Journal ArticleDOI
Bacillus subtilis Swarmer Cells Lead the Swarm, Multiply, and Generate a Trail of Quiescent Descendants.
Lina Hamouche,Soumaya Laalami,Adrian Daerr,Solène Song,I. Barry Holland,Simone J. Séror,Kassem Hamze,Harald Putzer +7 more
TL;DR: In situ, in situ that DNA replication, protein translation and peptidoglycan synthesis are primarily restricted to the swarmer cells at dendrite tips, showing that swarmers not only lead the population forward but continue to multiply as a source of all cells in the community.