O
Olivier Laprévote
Researcher at Paris Descartes University
Publications - 222
Citations - 7945
Olivier Laprévote is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Mass spectrometry & Mass spectrometry imaging. The author has an hindex of 44, co-authored 216 publications receiving 7244 citations. Previous affiliations of Olivier Laprévote include Centre national de la recherche scientifique & Institut de Chimie des Substances Naturelles.
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Journal ArticleDOI
Improvement of biological time-of-flight-secondary ion mass spectrometry imaging with a bismuth cluster ion source.
TL;DR: A new liquid metal ion gun filled with bismuth has been fitted to a time-of-flight—secondary ion mass spectrometer (TOF-SIMS) and the results show a great improvement of the imaging capabilities in terms of accessible mass range and useful lateral resolution.
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Tissue Molecular Ion Imaging by Gold Cluster Ion Bombardment
David Touboul,Frédéric Halgand,Alain Brunelle,Reinhard Kersting,Elke Tallarek,Birgit Hagenhoff,Olivier Laprévote +6 more
TL;DR: The use of gold cluster focused ion beams produced by a liquid metal ion gun in a TOF-SIMS mass spectrometer is shown to dramatically enhance secondary ion emission of phospholipids and peptides.
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imzML--a common data format for the flexible exchange and processing of mass spectrometry imaging data.
Thorsten Schramm,Alfons Hester,Ivo Klinkert,Jean-Pierre Both,Ron M. A. Heeren,Alain Brunelle,Olivier Laprévote,Nicolas Desbenoit,Marie-France Robbe,Markus Stoeckli,Bernhard Spengler,Andreas Römpp +11 more
TL;DR: The data format imzML was developed to allow the flexible and efficient exchange of MS imaging data between different instruments and data analysis software.
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Diversity Among Microbial Cyclic Lipopeptides: Iturins and Surfactins. Activity-Structure Relationships to Design New Bioactive Agents
TL;DR: Improved physical techniques such as 2D-NMR and mass spectrometry allowed to describe efficiently and rapidly the composition of cyclic lipopeptides even in mixtures containing several variants, and the role of residues was identified in the context of hydrophobic and electrostatic interactions that play a leader role.
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Biological tissue imaging with time-of-flight secondary ion mass spectrometry and cluster ion sources
TL;DR: Time-of-flight secondary ion mass spectrometry (TOF-SIMS) using liquid metal ion guns (LMIGs) is now sensitive enough to produce molecular-ion images directly from biological tissue samples, fully compatible with subsequent and complementary analyses like fluorescence microscopy, histochemical staining, or even matrix-assisted laser desorption/ionisation imaging.