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Katharina Fleischhauer
Researcher at MolMed
Publications - 133
Citations - 5532
Katharina Fleischhauer is an academic researcher from MolMed. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 30, co-authored 120 publications receiving 4915 citations.
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Journal ArticleDOI
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.
Maria Grazia Roncarolo,Silvia Gregori,Manuela Battaglia,Rosa Bacchetta,Katharina Fleischhauer,Megan K. Levings +5 more
TL;DR: Results from clinical protocols using Tr1 cells to modulate immune responses in vivo in autoimmunity, transplantation, and chronic inflammatory diseases will undoubtedly prove the biological relevance of these cells in immunotolerance.
Journal ArticleDOI
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I–II study
Fabio Ciceri,Chiara Bonini,Maria Teresa Lupo Stanghellini,Attilio Bondanza,Catia Traversari,Monica Salomoni,Lucia Turchetto,Scialini Colombi,Massimo Bernardi,Jacopo Peccatori,Alessandra Pescarollo,Paolo Servida,Zulma Magnani,Serena K. Perna,Veronica Valtolina,Fulvio Crippa,Luciano Callegaro,Elena Spoldi,Roberto Crocchiolo,Katharina Fleischhauer,Maurilio Ponzoni,Luca Vago,Silvano Rossini,Armando Santoro,Elisabetta Todisco,Jane F. Apperley,Eduardo Olavarria,Shimon Slavin,Eva M. Weissinger,Arnold Ganser,Michael Stadler,Evangelia Yannaki,Athanasios Fassas,Achilles Anagnostopoulos,Marco Bregni,Corrado Gallo Stampino,Paolo Bruzzi,Claudio Bordignon +37 more
TL;DR: Infusion of TK-cells might be effective in accelerating immune reconstitution, while controlling GVHD and protecting patients from late mortality in those who are candidates for haploidentical stem-cell transplantation.
Journal ArticleDOI
Loss of Mismatched HLA in Leukemia after Stem-Cell Transplantation
Luca Vago,Serena K. Perna,Monica Zanussi,Benedetta Mazzi,Cristina Barlassina,Maria Teresa Lupo Stanghellini,Nicola Flavio Perrelli,Cristian Cosentino,Federica Torri,Andrea Angius,Barbara Forno,Monica Casucci,Massimo Bernardi,Jacopo Peccatori,Consuelo Corti,Attilio Bondanza,Maurizio Ferrari,Silvano Rossini,Maria Grazia Roncarolo,Claudio Bordignon,Chiara Bonini,Fabio Ciceri,Katharina Fleischhauer +22 more
TL;DR: After transplantation of haploidentical hematopoietic stem cells and infusion of donor T cells, leukemic cells can escape from the donor's antileukemic T cells through the loss of the mismatched HLA haplotype, which leads to relapse.
Journal ArticleDOI
Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study
Katharina Fleischhauer,Bronwen E. Shaw,Bronwen E. Shaw,Ted Gooley,Mari Malkki,Peter G Bardy,Peter G Bardy,Jean Denis Bignon,Valérie Dubois,Mary M. Horowitz,J. Alejandro Madrigal,Yasuo Morishima,Machteld Oudshoorn,Olle Ringdén,Stephen R. Spellman,Andrea Velardi,Elisabetta Zino,Effie W. Petersdorf +17 more
TL;DR: A retrospective study compared outcomes between permissive and non-permissive HLA-DPB1 mismatches in unrelated-donor haemopoietic-cell transplantation to identify mismatches that might be tolerated and those that would increase risks after transplantation.