M
Mari Malkki
Researcher at Fred Hutchinson Cancer Research Center
Publications - 63
Citations - 3404
Mari Malkki is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Transplantation & Human leukocyte antigen. The author has an hindex of 27, co-authored 62 publications receiving 3079 citations.
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Journal ArticleDOI
HLA-C-dependent prevention of leukemia relapse by donor activating KIR2DS1
Jeffrey M. Venstrom,Gianfranco Pittari,Ted Gooley,Joseph H. Chewning,Stephen R. Spellman,Michael Haagenson,Meighan M. Gallagher,Mari Malkki,Effie W. Petersdorf,Bo Dupont,Katharine C. Hsu +10 more
TL;DR: Donor KIR2DS1 appeared to provide protection against relapse in an HLA-C-dependent manner, and donor KIR3DS1 was associated with reduced mortality.
Journal ArticleDOI
Major-Histocompatibility-Complex Class I Alleles and Antigens in Hematopoietic-Cell Transplantation
Effie W. Petersdorf,John A. Hansen,Paul J. Martin,Ann E. Woolfrey,Mari Malkki,Ted Gooley,Barry E. Storer,Eric Mickelson,Anajane G. Smith,Claudio Anasetti +9 more
TL;DR: HLA class I antigen mismatches that are serologically detectable confer an enhanced risk of graft failure after hematopoietic-cell transplantation.
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Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study
Katharina Fleischhauer,Bronwen E. Shaw,Bronwen E. Shaw,Ted Gooley,Mari Malkki,Peter G Bardy,Peter G Bardy,Jean Denis Bignon,Valérie Dubois,Mary M. Horowitz,J. Alejandro Madrigal,Yasuo Morishima,Machteld Oudshoorn,Olle Ringdén,Stephen R. Spellman,Andrea Velardi,Elisabetta Zino,Effie W. Petersdorf +17 more
TL;DR: A retrospective study compared outcomes between permissive and non-permissive HLA-DPB1 mismatches in unrelated-donor haemopoietic-cell transplantation to identify mismatches that might be tolerated and those that would increase risks after transplantation.
Journal ArticleDOI
Limits of HLA mismatching in unrelated hematopoietic cell transplantation
Effie W. Petersdorf,Claudio Anasetti,Paul J. Martin,Ted Gooley,Jerald P. Radich,Mari Malkki,Ann E. Woolfrey,Anajane G. Smith,Eric Mickelson,John A. Hansen +9 more
TL;DR: In this article, the authors examined the association of mortality with HLA-A, -B, -C, -DRB1, and -DQB1 mismatches in 948 patients who received a T-replete unrelated HCT for treatment of a marrow disorder.
Journal ArticleDOI
KIR Ligands and Prediction of Relapse after Unrelated Donor Hematopoietic Cell Transplantation for Hematologic Malignancy
Katharine C. Hsu,Ted Gooley,Mari Malkki,Clara Pinto-Agnello,Bo Dupont,Jean Denis Bignon,Martin Bornhäuser,Frank T. Christiansen,Alois Gratwohl,Yasuo Morishima,Machteld Oudshoorn,Olle Ringdén,Jon J. van Rood,Effie W. Petersdorf,Effie W. Petersdorf +14 more
TL;DR: Recipient homozygosity for HLA-B or -C epitopes that define KIR ligands is likely to be a predictive factor for leukemia relapse after myeloablative HCT from H LA-mismatched unrelated donors, but this effect was not observed in Hla-identical unrelated transplants.