K
Katherine Ferrell
Researcher at University of Utah
Publications - 21
Citations - 2446
Katherine Ferrell is an academic researcher from University of Utah. The author has contributed to research in topics: Protein subunit & Proteasome. The author has an hindex of 21, co-authored 21 publications receiving 2399 citations. Previous affiliations of Katherine Ferrell include Humboldt University of Berlin & Humboldt State University.
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Journal ArticleDOI
Purification of an 11 S regulator of the multicatalytic protease.
TL;DR: Activation appears to result from reversible association of regulator subunits with MCP, and activated MCP migrates slower on native acrylamide gels.
Journal ArticleDOI
A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits
Michael Seeger,Regine Kraft,Katherine Ferrell,Dawadschargal Bech-Otschir,Dumdey R,Rüdiger Schade,Colin Gordon,Michael Naumann,Wolfgang Dubiel +8 more
TL;DR: Three subunits of the new complex—Sgn3, Sgn5/JAB1, and Sgn6—exhibit sequence similarities to regulatory components of the 26S proteasome, which could indicate the existence of common substrate binding sites and the name JAB1‐containing signalosome is suggested.
Journal ArticleDOI
Regulatory subunit interactions of the 26S proteasome, a complex problem
TL;DR: Inspection of interactions of regulatory subunits with non-subunit proteins reveals patterns that suggest these interactions play a role in 26S proteasome regulation and localization.
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Molecular cloning and expression of a gamma-interferon-inducible activator of the multicatalytic protease.
TL;DR: The multicatalytic protease can be activated by two distinct multisubunit complexes, and synthesis of the activator subunit was induced by gamma interferon treatment of HeLa cells, which have implications for antigen presentation by class I major histocompatibility receptors.
Journal ArticleDOI
Subunit 4 of the 26 S protease is a member of a novel eukaryotic ATPase family.
TL;DR: Subunit 4 belongs to a recently identified eukaryotic ATPase family, which includes proteins involved in peroxisome formation, secretion, and human immunodeficiency virus gene expression as mentioned in this paper.