K
Kathleen-Rose Skelly
Researcher at Stanford University
Publications - 2
Citations - 145
Kathleen-Rose Skelly is an academic researcher from Stanford University. The author has contributed to research in topics: Enteroendocrine cell & Receptor. The author has an hindex of 2, co-authored 2 publications receiving 110 citations.
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Journal ArticleDOI
Suppression of Insulin Production and Secretion by a Decretin Hormone
Ronald W. Alfa,Sangbin Park,Kathleen-Rose Skelly,Gregory Poffenberger,Nimit Jain,Xueying Gu,Lutz Kockel,Jing Wang,Yinghua Liu,Alvin C. Powers,Alvin C. Powers,Alvin C. Powers,Seung K. Kim +12 more
TL;DR: Drosophila Limostatin is proposed as an index member of an ancient hormone class called decretins, which suppress insulin output and is expressed in islet β cells, and purified NMU suppresses insulin secretion from human islets.
Posted ContentDOI
Functional immune mapping with deep-learning enabled phenomics applied to immunomodulatory and COVID-19 drug discovery
Michael F. Cuccarese,Berton A. Earnshaw,Katie Heiser,Ben Fogelson,Chadwick T. Davis,Peter F. McLean,Hannah B. Gordon,Kathleen-Rose Skelly,Fiona L. Weathersby,Vlad Rodic,Ian K. Quigley,Elissa D. Pastuzyn,Brandon M. Mendivil,Nathan H. Lazar,Carl A. Brooks,Joseph Carpenter,Brandon L. Probst,Pamela Jacobson,Seth W. Glazier,Jes Ford,James D. Jensen,Nicholas D. Campbell,Michael A. Statnick,Adeline S. Low,Kirk R. Thomas,Anne E. Carpenter,Sharath S. Hegde,Ronald W. Alfa,Mason L. Victors,Imran S. Haque,Yolanda T. Chong,Christopher C. Gibson +31 more
TL;DR: Deep-learning-driven analysis of cellular morphology is applied to develop a scalable “phenomics” platform and its ability to identify dose-dependent, high-dimensional relationships among and between immunomodulators, toxins, pathogens, genetic perturbations, and small and large molecules at scale is demonstrated.