K
Katie L. Thompson
Researcher at Mayo Clinic
Publications - 1
Citations - 133
Katie L. Thompson is an academic researcher from Mayo Clinic. The author has contributed to research in topics: CD38 & Inflammation. The author has an hindex of 1, co-authored 1 publications receiving 34 citations.
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CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels.
Claudia C.S. Chini,Thais Peclat,Gina M. Warner,Sonu Kashyap,Jair Machado Espindola-Netto,Guilherme C. de Oliveira,Lilian S Gomez,Kelly A. Hogan,Mariana G. Tarragó,Amrutesh S. Puranik,Amrutesh S. Puranik,Guillermo Agorrody,Katie L. Thompson,Kevin Dang,Starlynn Clarke,Bennett G. Childs,Karina S. Kanamori,Micaela A. Witte,Paola Vidal,Anna L. Kirkland,Marco De Cecco,Marco De Cecco,Karthikeyani Chellappa,Melanie R. McReynolds,Connor Jankowski,Tamara Tchkonia,James L. Kirkland,John M. Sedivy,Jan M. van Deursen,Darren J. Baker,Wim Van Schooten,Joshua D. Rabinowitz,Joseph A. Baur,Eduardo N. Chini +33 more
TL;DR: It is demonstrated that senescence-induced inflammation promotes accumulation of CD38 in immune cells that, through its ecto-enzymatic activity, decreases levels of NMN and NAD+.