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Katja Becker

Researcher at University of Giessen

Publications -  381
Citations -  18279

Katja Becker is an academic researcher from University of Giessen. The author has contributed to research in topics: Plasmodium falciparum & Thioredoxin. The author has an hindex of 68, co-authored 362 publications receiving 16574 citations. Previous affiliations of Katja Becker include University of Marburg & Heidelberg University.

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Oxidative stress in malaria parasite-infected erythrocytes: Host-parasite interactions

TL;DR: The presently available knowledge on sources and detoxification pathways of reactive oxygen species in malaria parasite-infected red cells, on clinical aspects of redox metabolism and redox-related mechanisms of drug action as well as future prospects for drug development is summarized.
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Human Placenta Thioredoxin Reductase: ISOLATION OF THE SELENOENZYME, STEADY STATE KINETICS, AND INHIBITION BY THERAPEUTIC GOLD COMPOUNDS *

TL;DR: In its physiological, NADPH-reduced form, the enzyme is strongly inhibited by organic gold compounds that are widely used in the treatment of rheumatoid arthritis; for auranofin, the K i was 4 nm when measured in the presence of 50 μmthioredoxin.
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The thioredoxin system—From science to clinic

TL;DR: This review of the thioredoxin system will present and evaluate the preclinical and clinical results available today, and current trends in drug development are emphasized.
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Substitution of the Thioredoxin System for Glutathione Reductase in Drosophila melanogaster

TL;DR: The absence of glutathione reductase in Drosophila melanogaster is demonstrated, a new type of thioredoxin reduct enzyme is identified, and evidence that a thiOREDoxin system supports GSSG reduction is provided, suggesting that antioxidant defense in Dosophila, and probably in related insects, differs fundamentally from that in other organisms.