K
Katja Ott
Researcher at Heidelberg University
Publications - 49
Citations - 1838
Katja Ott is an academic researcher from Heidelberg University. The author has contributed to research in topics: Cancer & Neoadjuvant therapy. The author has an hindex of 22, co-authored 49 publications receiving 1623 citations. Previous affiliations of Katja Ott include Technische Universität München.
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Book ChapterDOI
Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract.
TL;DR: The studies point to promising markers with potential use for chemotherapy response prediction of adenocarcinomas of the upper gastrointestinal tract, but prospective studies for validation are necessary.
Journal ArticleDOI
Serum microRNA profiles as prognostic or predictive markers in the multimodality treatment of patients with gastric cancer.
Leila Sisic,Daniel Vallböhmer,Nikolas H. Stoecklein,Susanne Blank,Thomas Schmidt,C Driemel,Birte Möhlendick,Wolfram T. Knoefel,Margarete Odenthal,Katja Ott +9 more
TL;DR: A pilot study to characterize the serum microRNA (miRNA/miR) profile of gastric cancer patients undergoing multimodality therapy failed to identify a prognostic or predictive value in selected miRNAs using single RT-PCR measurements, however, microarray results revealed a differential microRNA expression profile depending on the histopathological regression.
Journal ArticleDOI
Shared genetic etiology of obesity-related traits and Barrett's esophagus/adenocarcinoma: Insights from genome-wide association studies
Anne C. Böhmer,Julian Hecker,Julia Schröder,Puya Gharahkhani,Andrea May,Christian Gerges,Mario Anders,Jessica Becker,Timo Hess,Nicole Kreuser,René Thieme,Tania Noder,Marino Venerito,Lothar Veits,Thomas Schmidt,Claudia Fuchs,Jakob R. Izbicki,Arnulf H. Hölscher,Arne Dietrich,Yusef Moulla,Orestis Lyros,Hauke Lang,Dietmar Lorenz,Brigitte Schumacher,Rupert Mayershofer,Yogesh K. Vashist,Katja Ott,Michael Vieth,Josef Weismüller,Susanne Moebus,Michael Knapp,Horst Neuhaus,Thomas Rösch,Christian Ell,Markus M. Nöthen,David C. Whiteman,Ian Tomlinson,Janusz Jankowski,Janusz Jankowski,Rebecca C. Fitzgerald,Claire Palles,Thomas L. Vaughan,Ines Gockel,Aaron P. Thrift,Heide Loehlein Fier,Johannes Schumacher +45 more
TL;DR: Evidence for sex-specific genetic correlations that might reflect specific biological mecha-nisms is provided, demonstrating that shared genetic factors are particularly relevant in progression from BE to EA.
Journal ArticleDOI
Neoadjuvante Therapie im oberen Gastrointestinaltrakt
Katja Ott,F. Lordick +1 more
TL;DR: Peri-operative chemotherapy significantly improves the survival of patients with adenocarcinoma of the stomach and of the gastro-esophageal junction and two randomized studies that have been performed in Europe have shown that multimodal treatment can improve the outcome in comparison to surgery alone.
Journal ArticleDOI
Importance of PET in Surgery of Esophageal Cancer
TL;DR: Early response monitoring during preoperative chemotherapy has shown promising results in prospective single center trials (MUNICON I/II) during chemotherapy of adenocarcinoma of the esophagogastric junction (AEG), but needs to be validated in prospective multicenter trails.