K
Kay E. Davies
Researcher at University of Oxford
Publications - 580
Citations - 40236
Kay E. Davies is an academic researcher from University of Oxford. The author has contributed to research in topics: Duchenne muscular dystrophy & Dystrophin. The author has an hindex of 100, co-authored 573 publications receiving 38462 citations. Previous affiliations of Kay E. Davies include Case Western Reserve University & Technische Universität München.
Papers
More filters
Journal ArticleDOI
Deletion of smn-1, the Caenorhabditis elegans ortholog of the spinal muscular atrophy gene, results in locomotor dysfunction and reduced lifespan
Michael Briese,Behrooz Esmaeili,Sandrine Fraboulet,Sandrine Fraboulet,Emma C. Burt,Stefanos Christodoulou,Paula R. Towers,Kay E. Davies,David B. Sattelle +8 more
TL;DR: The deletion mutant smn-1(ok355) provides a useful platform for functional analysis of an invertebrate ortholog of the human SMN protein.
Journal ArticleDOI
Sex chromosome positions in human interphase nuclei as studied by in situ hybridization with chromosome specific DNA probes
TL;DR: The data demonstrate the potential use of chromosome-specific repetitive DNA probes to study the problem of interphase chromosome topography and indicate a large variability of the distances between the sex chromosomes in male and female interphase nuclei.
Journal ArticleDOI
Utrophin: A potential replacement for dystrophin?
TL;DR: If this is the case, it may be possible to modify the regulation of utrophin expression as an alternative route to dystrophin gene therapy for sufferers of DMD and/or BMD.
Journal ArticleDOI
Direct interaction of Smn with dp103, a putative RNA helicase: a role for Smn in transcription regulation?
TL;DR: It is suggested that the interaction between SMN and DP103 is further evidence for a role for SMN in transcriptional regulation and that SMN may be involved in the regulation of neuron-specific genes essential in neuronal development.
Journal ArticleDOI
Characterisation of alpha-dystrobrevin in muscle
TL;DR: Results indicate that alpha-dystrobrevin-1 is not involved in the phosphorylation-dependent, early stages of receptor clustering, but rather in the stabilisation and maturation of clusters, possibly via an interaction with utrophin.