K
Kazuo T. Nakamura
Researcher at Showa University
Publications - 111
Citations - 1931
Kazuo T. Nakamura is an academic researcher from Showa University. The author has contributed to research in topics: RNase P & Anomer. The author has an hindex of 25, co-authored 111 publications receiving 1822 citations. Previous affiliations of Kazuo T. Nakamura include Nagasaki University.
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Identification of regions in which positive selection may operate in S-RNase of Rosaceae: implication for S-allele-specific recognition sites in S-RNase.
Takeshi Ishimizu,Toshinori Endo,Yumi Yamaguchi-Kabata,Kazuo T. Nakamura,Fumio Sakiyama,Shigemi Norioka +5 more
TL;DR: Window analysis of the numbers of synonymous and non‐synonymous substitutions in rosaceous S‐RNases detected four regions with an excess of dN over dS in which positive selection may operate (PS regions).
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SDR Structure, Mechanism of Action, and Substrate Recognition
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Structural basis for recognition of 2′,5′-linked oligoadenylates by human ribonuclease L
Nobutada Tanaka,Masayuki Nakanishi,Yoshio Kusakabe,Yoshikuni Goto,Yukio Kitade,Kazuo T. Nakamura +5 more
TL;DR: The crystal structure of the N‐terminal ankyrin repeat domain (ANK) of human RNase L complexed with the activator 2‐5A is reported, which is the first structural view of an ankyrIn repeat structure directly interacting with a nucleic acid, rather than with a protein.
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Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum
Tomonobu Umeda,Nobutada Tanaka,Yoshio Kusakabe,Masayuki Nakanishi,Yukio Kitade,Kazuo T. Nakamura +5 more
TL;DR: In this article, the crystal structures of fosmidomycin-bound complete quaternary complexes of PfDXR were reported, showing that an intrinsic flexibility of the Pf DXR molecule accounts for an induced-fit movement to accommodate the bound inhibitor in the active site and a cis arrangement of the oxygen atoms of the hydroxamate group of the binding inhibitor is essential for tight binding of the inhibitor to the active-site metal.
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Vibrational spectra and structures of zinc carboxylates I. Zinc acetate dihydrate
Tsutomu Ishioka,Youko Shibata,Mizuki Takahashi,Isao Kanesaka,Yasuyuki Kitagawa,Kazuo T. Nakamura +5 more
TL;DR: In this article, the crystal structure of zinc acetate dihydrate was re-refined by X-ray diffraction analysis of the single crystal, and the monoclinic cell dimensions were revised as a=14.394 (3), b=5.330 (2), c=10.962 (3) A and β=99.8 (2)° with Z=4.