K
Kazuya Miyagi
Researcher at University of the Ryukyus
Publications - 72
Citations - 1715
Kazuya Miyagi is an academic researcher from University of the Ryukyus. The author has contributed to research in topics: Photonic-crystal fiber & Dispersion (optics). The author has an hindex of 19, co-authored 71 publications receiving 1545 citations.
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Critical role of Vα14+ natural killer T cells in the innate phase of host protection against Streptococcus pneumoniae infection
Kazuyoshi Kawakami,Natsuo Yamamoto,Yuki Kinjo,Kazuya Miyagi,Chikara Nakasone,Kaori Uezu,Takeshi Kinjo,Toshinori Nakayama,Masaru Taniguchi,Atsushi Saito +9 more
TL;DR: MCP‐1‐dependent recruitment of Vα14+ NKT cells and their critical role in early host protection against S. pneumoniae by promoting the trafficking of neutrophils to the site of infection are demonstrated.
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Monocyte Chemoattractant Protein-1-Dependent Increase of Vα14 NKT Cells in Lungs and Their Roles in Th1 Response and Host Defense in Cryptococcal Infection
Kazuyoshi Kawakami,Yuki Kinjo,Kaori Uezu,Satomi Yara,Kazuya Miyagi,Yoshinobu Koguchi,Toshinori Nakayama,Masaru Taniguchi,Atsushi Saito +8 more
TL;DR: It is demonstrated that NKT cells, especially Vα14+ subset, accumulated in a MCP-1-dependent manner in the lungs after infection with C. neoformans and played an important role in the development of Th1 response and host resistance to this fungal pathogen.
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Lower expression of Th1-related cytokines and inducible nitric oxide synthase in mice with streptozotocin-induced diabetes mellitus infected with Mycobacterium tuberculosis.
Shin Yamashiro,Kazuyoshi Kawakami,Kaori Uezu,Tetsu Kinjo,Kazuya Miyagi,Katsunori Nakamura,Saito A +6 more
TL;DR: The results suggest that the reduced production of Th1‐related cytokines and NO account for the hampered host defense against M. tuberculosis infection under diabetic conditions.
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Role of interferon-γ in Vα14+ natural killer T cell-mediated host defense against Streptococcus pneumoniae infection in murine lungs
Masashi Nakamatsu,Natsuo Yamamoto,Masumitsu Hatta,Chikara Nakasone,Takeshi Kinjo,Kazuya Miyagi,Kaori Uezu,Kiwamu Nakamura,Kiwamu Nakamura,Toshinori Nakayama,Masaru Taniguchi,Yoichiro Iwakura,Mitsuo Kaku,Jiro Fujita,Kazuyoshi Kawakami,Kazuyoshi Kawakami +15 more
TL;DR: The results demonstrated that IFN-γ plays an important role in the neutrophil-mediated host protective responses against pneumococcal infection promoted by Vα14+ NKT cells.
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Accumulation of γδ T cells in the lungs and their regulatory roles in Th1 response and host defense against pulmonary infection with Cryptococcus neoformans
Kaori Uezu,Kazuyoshi Kawakami,Kazuya Miyagi,Yuki Kinjo,Takeshi Kinjo,Hiromichi Ishikawa,Atsushi Saito +6 more
TL;DR: It is demonstrated that γδ T cells accumulated in the lungs in a manner different from NK and NKT cells after cryptococcal infection and played a down-modulatory role in the development of Th1 response and host resistance against this fungal pathogen.