K
Ke Li
Researcher at Central South University
Publications - 3
Citations - 28
Ke Li is an academic researcher from Central South University. The author has contributed to research in topics: Ubiquitin ligase & Peroxisome proliferator-activated receptor. The author has an hindex of 2, co-authored 3 publications receiving 10 citations.
Papers
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Journal ArticleDOI
TRIB3 promotes MYC-associated lymphoma development through suppression of UBE3B-mediated MYC degradation.
Ke Li,Feng Wang,Zhao-na Yang,Ting-ting Zhang,Yu-fen Yuan,Chen-xi Zhao,Zaiwuli Yeerjiang,Bing Cui,Fang Hua,Xiaoxi Lv,Xiaowei Zhang,Jiao-jiao Yu,Shan-Shan Liu,Jin-mei Yu,Shuang Shang,Yang Xiao,Zhuo-Wei Hu,Zhuo-Wei Hu +17 more
TL;DR: It is reported that high expression of tribbles homologue 3 (TRIB3) positively correlates with elevated MyC expression in lymphoma specimens; TRIB3 deletion attenuates the initiation and progression of MYC-driven lymphoma by reducing MYC expression.
Journal ArticleDOI
PML-RARα interaction with TRIB3 impedes PPARγ/RXR function and triggers dyslipidemia in acute promyelocytic leukemia.
TL;DR: The critical role of the PML-RARα/PPARγ/TRIB3 axis in the development of dyslipidemia in APL patients is revealed, potentially conferring a rationale for combining ATRA/arsenic with the PPAR activator for APL treatment.
Patent
Polypeptide capable of specifically binding with trb3 protein, screening method therefor, and identification and use thereof
TL;DR: In this paper, three polypeptides capable of specifically binding with human pseudo kinase tribbles 3 (TRB3) have been revealed, which can be used for development of vaccines or drugs for inhibiting the growth and transfer of tumor cells.