K
Keefe B. Manning
Researcher at Pennsylvania State University
Publications - 120
Citations - 2301
Keefe B. Manning is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Pulsatile flow & Particle image velocimetry. The author has an hindex of 22, co-authored 108 publications receiving 1888 citations. Previous affiliations of Keefe B. Manning include Virginia Commonwealth University & Penn State Milton S. Hershey Medical Center.
Papers
More filters
Journal ArticleDOI
Hydrodynamics in Acute Ischemic Stroke Catheters Under Static and Cyclic Aspiration Conditions
TL;DR: For future investigations of cyclic aspiration AIS therapy, the best options are to use large inner diameter and low compliance catheters operating at lower cyclic frequencies to generate the greatest mean and oscillating forces on lodged thromboemboli.
Journal ArticleDOI
Modifying a Tilting Disk Mechanical Heart Valve Design to Improve Closing Dynamics
TL;DR: Initial findings suggest that changes to the structure or physical properties of well established mechanical valves, such as the one described here, can reduce closure induced hemolysis by minimizing cavitation.
Journal ArticleDOI
Shaft/shaft-seal interface characteristics of a multiple disk centrifugal blood pump.
TL;DR: The conclusions made from the results indicate that both the tested shaft seal materials and shaft materials are not ideal candidates to be used for the MDCP.
Journal ArticleDOI
Characterizing the HeartMate II Left Ventricular Assist Device Outflow Using Particle Image Velocimetry
TL;DR: In vitro studies were performed to measure the flow located within the HMII outlet cannula under both steady and physiological conditions and generated principal Reynolds stresses that are, at times, orders of magnitude higher than those needed to unfurl vWF, potentially impacting its physiological function.
Journal ArticleDOI
Refining a numerical model for device-induced thrombosis and investigating the effects of non-Newtonian blood models
TL;DR: In this article, the authors improved the existing thrombosis model by modifying the chemical platelet activation function so that ADP activates platelets, and modifying the function describing thrombus deposition and growth.