K
Keefe B. Manning
Researcher at Pennsylvania State University
Publications - 120
Citations - 2301
Keefe B. Manning is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Pulsatile flow & Particle image velocimetry. The author has an hindex of 22, co-authored 108 publications receiving 1888 citations. Previous affiliations of Keefe B. Manning include Virginia Commonwealth University & Penn State Milton S. Hershey Medical Center.
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Journal ArticleDOI
Near field flow characteristics of the Bjork-Shiley Monostrut valve in a modified single shot valve chamber.
TL;DR: This study provides further evidence that stable bubble formation may stem from the intense vortex cavitation occurring during valve closure and rebound, which intensifies during rebound and dissipates during the final closing cycle.
Journal ArticleDOI
Flow Visualization of a Pediatric Ventricular Assist Device During Stroke Volume Reductions Related to Weaning
TL;DR: SV reduction is a viable option for flow reduction during weaning, however, it does lead to significant changes to the device flow field and future studies are needed to develop operational protocols for the PVAD during bridge-to-recovery.
Journal ArticleDOI
Development of a platelet adhesion transport equation for a computational thrombosis model
TL;DR: This work introduces a surface adherent platelet transport equation into a continuum model to account for the biomaterial interface/blood interaction and provides good evidence that this transport equation can be used to express the relationship between blood and a biomaterial if the correct platelet adhesion characteristics are known for the biomass.
Journal ArticleDOI
A fluid dynamics study in a 50 cc pulsatile ventricular assist device: influence of heart rate variability.
TL;DR: Changes in in vivo operating conditions strongly influence wall shear rates within the Penn State pulsatile LVAD, and likely play a significant role in thrombus deposition.
Book ChapterDOI
Patient-Specific Model Generation and Simulation for Pre-operative Surgical Guidance for Pulmonary Embolism Treatment
Shankar Prasad Sastry,Jibum Kim,Suzanne M. Shontz,Brent A. Craven,Frank C. Lynch,Keefe B. Manning,Thap Panitanarak +6 more
TL;DR: A computational pipeline that can be used to generate patient-specific geometric models and computational meshes of the IVC and IVC filter for various IVC anatomies based on the patient’s computer tomography (CT) images is proposed.