K
Kei Shinoda
Researcher at Saitama Medical University
Publications - 245
Citations - 4866
Kei Shinoda is an academic researcher from Saitama Medical University. The author has contributed to research in topics: Vitrectomy & Visual acuity. The author has an hindex of 36, co-authored 230 publications receiving 4388 citations. Previous affiliations of Kei Shinoda include Oita University & Kyorin University.
Papers
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Journal ArticleDOI
Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degeneration.
Yutaka Imamura,Setsuko Noda,Kouhei Hashizume,Kei Shinoda,Mineko Yamaguchi,Satoshi Uchiyama,Takahiko Shimizu,Yutaka Mizushima,Takuji Shirasawa,Kazuo Tsubota +9 more
TL;DR: It is shown that mice deficient in Cu, Zn-superoxide dismutase (SOD1) have features typical of age-related macular degeneration in humans, and these findings provide evidence for the free radical theory of aging.
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Angiotensin II Type 1 Receptor Signaling Contributes to Synaptophysin Degradation and Neuronal Dysfunction in the Diabetic Retina
Toshihide Kurihara,Yoko Ozawa,Norihiro Nagai,Kei Shinoda,Kousuke Noda,Yutaka Imamura,Kazuo Tsubota,Hideyuki Okano,Yuichi Oike,Susumu Ishida +9 more
TL;DR: These data indicate the first molecular evidence of the RAS-induced synaptophysin degradation and neuronal dysfunction in the diabetic retina, suggesting the possibility of the AT1R blockade as a novel neuroprotective treatment for diabetic retinopathy.
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Neuroprotective effects of angiotensin II type 1 receptor (AT1R) blocker, telmisartan, via modulating AT1R and AT2R signaling in retinal inflammation
Toshihide Kurihara,Yoko Ozawa,Kei Shinoda,Norihiro Nagai,Makoto Inoue,Yuichi Oike,Kazuo Tsubota,Susumu Ishida,Hideyuki Okano +8 more
TL;DR: Investigating the retinal neural damage that occurs during inflammation and the therapeutic effects of the angiotensin II type 1 receptor (AT1R) blocker, telmisartan, using a model of endotoxin-induced uveitis found that retinal protein expression and visual function are both disturbed by inflammation.
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Retinal Dysfunction and Progressive Retinal Cell Death in SOD1-Deficient Mice
Kouhei Hashizume,Manabu Hirasawa,Yutaka Imamura,Setsuko Noda,Takahiko Shimizu,Kei Shinoda,Toshihide Kurihara,Kousuke Noda,Yoko Ozawa,Susumu Ishida,Yozo Miyake,Takuji Shirasawa,Kazuo Tsubota +12 more
TL;DR: The results indicate that Sod1(-/-) mice may be a good model system in which to study the mechanism of reactive oxygen species-mediated retinal degeneration.
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Comparison of scleral buckling and vitrectomy for retinal detachment resulting from flap tears in superior quadrants.
TL;DR: Primary vitrectomy was as successful as scleral buckling for treating superior rhegmatogenous retinal detachment and even though the high incidence of postoperative cataract formation was the major drawback, vit rectomy had some advantages over sclal buckling.