Kelley A. Hutcheson

TL;DR: In rabbits in which myoblasts were incorporated, myocardial performance was improved and the ability to regeneratefunctioning muscle after autologous myoblast transplantation could have a important effect on patients after acuteMyocardial infarction.

TL;DR: Morbidity and mortality of EG are significant, but most complications, including anastomotic leak, are not independent predictors of mortality.

TL;DR: A molecular pathway in which calcineurin and MEF2 participate in the adaptive mechanisms by which skeletal myofibers acquire specialized contractile and metabolic properties as a function of changing patterns of muscle contraction is delineated.

TL;DR: Comparing indices of regional contractile (systolic) and diastolic myocardial performance following transplantation of either autologous skeletal myoblasts or dermal fibroblasts into chronically injured rabbit heart suggests that both contractile and noncontractile cells can improve regional material properties or structural integrity of terminally injured heart.

TL;DR: Cellular cardiomyoplasty, a potential therapeutic option for ischemic heart disease, appears to reverse diastolic creep and thus may represent a clinical alternative to transplantation in the near future.