K
Kelly S. Lundberg
Researcher at Stratagene
Publications - 2
Citations - 709
Kelly S. Lundberg is an academic researcher from Stratagene. The author has contributed to research in topics: Hot start PCR & Germline mutation. The author has an hindex of 2, co-authored 2 publications receiving 686 citations.
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Journal ArticleDOI
High-fidelity amplification using a thermostable DNA polymerase isolated from Pyrococcus furiosus
Kelly S. Lundberg,Daniel D. Abrahms Apartment C Shoemaker,Michael W. W. Adams,Jay M. Short,Joseph A. Sorge,Eric J. Mathur +5 more
TL;DR: These studies demonstrate that the error rate per nucleotide induced in the 182 known detectable sites of the lacI gene was 1.6 x 10(-6) for Pfu DNA polymerase, a greater than tenfold improvement over the 2.0 x 10 (-5) error rate for Taq DNA polymerases.
Journal ArticleDOI
Spontaneous mutations in lacI-containing λ lysogens derived from transgenic mice: The observed patterns differ in liver and spleen
Antje Knöll,David P. Jacobson,Patricia L. Kretz,Kelly S. Lundberg,Jay M. Short,Steve S. Sommer +5 more
TL;DR: Evidence is provided that the spontaneous pattern of mutation is tissue specific and the high frequency of transversions at CpG suggests the need to reevaluate the mechanisms by which mutations occur at this methylated dinucleotide.