K
Kendelle J. Murphy
Researcher at Garvan Institute of Medical Research
Publications - 30
Citations - 1058
Kendelle J. Murphy is an academic researcher from Garvan Institute of Medical Research. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 11, co-authored 23 publications receiving 569 citations. Previous affiliations of Kendelle J. Murphy include University of New South Wales.
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Journal ArticleDOI
MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma
Lesley Castillo,Adelaide I. J. Young,Amanda Mawson,Pia Schafranek,Angela Steinmann,Danielle Nessem,Ashleigh Parkin,Amber L. Johns,Amber L. Johns,Angela Chou,Andrew M. K. Law,Morghan C. Lucas,Kendelle J. Murphy,Niantao Deng,Niantao Deng,David Gallego-Ortega,David Gallego-Ortega,Catherine E Caldon,Catherine E Caldon,Paul Timpson,Paul Timpson,Marina Pajic,Marina Pajic,Christopher J. Ormandy,Christopher J. Ormandy,Samantha R. Oakes,Samantha R. Oakes +26 more
TL;DR: It is suggested that MCL-1 antagonism, while reducing cell viability, may have an additional benefit in increasing the antimetastatic efficacy of dasatinib for the treatment of PDAC.
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Dynamic Stromal Alterations Influence Tumor-Stroma Crosstalk to Promote Pancreatic Cancer and Treatment Resistance.
Kendelle J. Murphy,Kendelle J. Murphy,Cecilia R. Chambers,Cecilia R. Chambers,David Herrmann,David Herrmann,Paul Timpson,Paul Timpson,Brooke A. Pereira,Brooke A. Pereira +9 more
TL;DR: In this paper, the authors explore the prognostic and functional value of the stromal compartment in predicting outcomes and clinical prognosis in pancreatic ductal adenocarcinoma (PDAC).
Journal ArticleDOI
Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions
Jaimy Jose,Monira Hoque,J D Engel,Syed Sultan Beevi,Mohamed Othman Wahba,Mariya Ilieva Georgieva,Kendelle J. Murphy,William E. Hughes,Blake J. Cochran,Albert Lu,Francesc Tebar,Andrew J. Hoy,Paul Timpson,Kerry-Anne Rye,Carlos Enrich,Carles Rentero,Thomas Grewal +16 more
TL;DR: In this paper , the authors demonstrate that LDL stimulates A431 squamous epithelial carcinoma and Chinese hamster ovary (CHO) cell migration and invasion in 3D environments, using organotypic assays.
Journal ArticleDOI
Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions
Jaimy Jose,Monira Hoque,J D Engel,Syed Sultan Beevi,Mohamed Othman Wahba,Mariya Ilieva Georgieva,Kendelle J. Murphy,William E. Hughes,Blake J. Cochran,Albert Lu,Francesc Tebar,Andrew J. Hoy,Paul Timpson,Kerry-Anne Rye,Carlos Enrich,Carles Rentero,Thomas Grewal +16 more
TL;DR: In this article , the authors demonstrate that LDL stimulates A431 squamous epithelial carcinoma and Chinese hamster ovary (CHO) cell migration and invasion in 3D environments, using organotypic assays.
Journal ArticleDOI
Quantifying and visualising the nuances of cellular dynamics in vivo using intravital imaging.
Kendelle J. Murphy,Daniel A Reed,Michael Trpceski,David Herrmann,David Herrmann,Paul Timpson,Paul Timpson +6 more
TL;DR: In this paper, the authors highlight recent advances in the field of intravital microscopy, touching upon advances in awake versus anaesthesia-based approaches, as well as the integration of biosensors into Intravital Imaging.