K
Kenichi Ishii
Researcher at University of Tokyo
Publications - 44
Citations - 1316
Kenichi Ishii is an academic researcher from University of Tokyo. The author has contributed to research in topics: Innate immune system & Immune system. The author has an hindex of 20, co-authored 42 publications receiving 1072 citations. Previous affiliations of Kenichi Ishii include Panasonic & RMIT University.
Papers
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Journal ArticleDOI
Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane
Hiroshi Hamamoto,Makoto Urai,Makoto Urai,Kenichi Ishii,Jyunichiro Yasukawa,Atmika Paudel,Motoki Murai,Takuya Kaji,Takefumi Kuranaga,Kenji Hamase,Takashi Katsu,Jie Su,Tatsuo Adachi,Ryuji Uchida,Hiroshi Tomoda,Maki K. Yamada,Manabu Souma,Hiroki Kurihara,Masayuki Inoue,Kazuhisa Sekimizu +19 more
TL;DR: Lysocin E interacted with menaquinone in the bacterial membrane to achieve its potent bactericidal activity, a mode of action distinct from that of any other known antibiotic, indicating that lysOCin E comprises a new class of antibiotic.
Posted ContentDOI
Virological characteristics of SARS-CoV-2 BA.2 variant
Daichi Yamasoba,Izumi Kimura,Hesham Nasser,Yuhei Morioka,Naganori Nao Nao,Jumpei Ito,Keiya Uriu,Masumi Tsuda,Jiří Zahradník,Kotaro Shirakawa,Rigel Suzuki,Mai Kishimoto,Yusuke Kosugi,Kouji Kobiyama,Teppei Hara,Mako Toyoda,Yurie Tanaka,Erika P. Butlertanaka,R. Shimizu,H. Ito,Lei Wang,Yoshitaka Oda,Yasuko Orba,Michihito Sasaki,Kayoko Nagata,Kumiko Yoshimatsu,Hiroyuki Asakura,Mami Nagashima,Kenji Sadamasu,Kazuhisa Yoshimura,Jin Kuramochi,Motoaki Seki,Ryoji Fujiki,Atsushi Kaneda,Tadanaga Shimada,Taka-aki Nakada,Seiichiro Sakao,Takuji Suzuki,Takamasa Ueno,Akifumi Takaori-Kondo,Kenichi Ishii,Gideon Schreiber,Hirofumi Sawa,Akatsuki Saito,Takashi Irie,Shinya Tanaka,Keita Matsuno,Takasuke Fukuhara,Terumasa Ikeda,Kei Sato +49 more
TL;DR: The authors' multiscale investigations suggest that the risk of BA.1.2 for global health is potentially higher than that of BA, and furthermore, infection experiments using hamsters show that BA.2 is more pathogenic than BA.
Journal ArticleDOI
Activation of the silkworm cytokine by bacterial and fungal cell wall components via a reactive oxygen species-triggered mechanism.
TL;DR: It is demonstrated that bacterial and fungal cell wall components peptidoglycan and glucan stimulate muscle contraction via activation of PP in the hemolymph, followed by the activation of serine protease, which mediates the PP processing reaction and leads to defensive responses.
Journal ArticleDOI
Insect cytokine paralytic peptide (PP) induces cellular and humoral immune responses in the silkworm Bombyx mori.
Kenichi Ishii,Hiroshi Hamamoto,Manabu Kamimura,Yuki Nakamura,Hiroaki Noda,Katsutoshi Imamura,Kazuei Mita,Kazuhisa Sekimizu +7 more
TL;DR: It is suggested that PP acts on multiple tissues in silkworm larvae and acutely activates cellular and humoral immune responses, leading to host protection against infection.
Patent
Glass antenna system for an automobile
TL;DR: A glass antenna system for an automobile comprises a main antenna disposed at an upper part of a glass plate for a rear window of the automobile and a defogging electric heating element disposed below and separate from the main antenna and comprising a plurality of heating strips and a pair of bus bars for supplying electricity to the heating strips.