K
Kenneth D. Laxer
Researcher at University of California, San Francisco
Publications - 90
Citations - 4878
Kenneth D. Laxer is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Epilepsy & Temporal lobe. The author has an hindex of 42, co-authored 87 publications receiving 4742 citations. Previous affiliations of Kenneth D. Laxer include University of California, Berkeley & California Pacific Medical Center.
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Journal ArticleDOI
Calcium-binding protein (calbindin-D28K) and parvalbumin immunocytochemistry in the normal and epileptic human hippocampus.
TL;DR: The calcium‐binding proteins calbindin‐D28K (CaBP) and parvalbumin (PV) were localized in the “normal” and “epileptic” human hippocampus to address the possible relationship between the expression of these constitutive cytosolic calcium‐ binding proteins and the resistance or selective vulnerability of different hippocampal neuron populations in temporal lobe epilepsy.
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Neuron loss localizes human temporal lobe epilepsy by in vivo proton magnetic resonance spectroscopic imaging
TL;DR: Preliminary results suggest that 1H‐MRSI can accurately localize temporal lobe epileptogenic foci in patients with medically refractory unilateral complex partial seizures and is a useful tool for the noninvasive clinical assessment of intractable focal epilepsy.
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Magnetoencephalography in partial epilepsy : Clinical yield and localization accuracy
Robert C. Knowlton,Kenneth D. Laxer,Michael J. Aminoff,Timothy P.L. Roberts,Stephen T. C. Wong,Howard A. Rowley +5 more
TL;DR: MEG can reliably localize sources of spike discharges in patients with temporal and extratemporal lobe epilepsy, as defined by all clinical and EEG information.
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Spatio-temporal correlations in human gamma band electrocorticograms
Vinod Menon,Walter J. Freeman,B. A. Cutillo,John E. Desmond,M. F. Ward,Steven L. Bressler,Kenneth D. Laxer,Nicholas M. Barbaro,Alan Gevins +8 more
TL;DR: The findings suggest that the surface diameters of domains of spatially correlated activity underlying perceptual categorization in human gamma band ECoG are limited to less than 2 cm and that the intermittent synchronization observed across separations of 1 cm and 1.4 cm is not solely due to volume conduction.
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Felbamate A double‐blind controlled trial in patients undergoing presurgical evaluation of partial seizures
Bourgeois Bourgeois,Ilo E. Leppik,James Chris Sackellares,Kenneth D. Laxer,Ronald P. Lesser,J. A. Messenheimer,Lynn D. Kramer,Marc Kamin,A. Rosenberg +8 more
TL;DR: The ability of felbamate to quickly and safely reduce the occurrence of frequent partial-onset seizures and maintain effective seizure control following reductions in the dosages of standard antiepileptic drugs is demonstrated.