Kenneth H. Wolfe

TL;DR: In silico analysis of the genome sequence of C. elegans B9769, which contains 32 genes putatively coding for CYPs, the first report of a xenobiotic-biotransforming CYP from this biotechnologically important fungus is reported.

TL;DR: The genome of Zygosaccharomyces strain MT15, an isolate from Maotai‐flavor Chinese liquor fermentation, is found to be an interspecies hybrid and it is found that the half‐sibling species Z. parabailii and Z. pseudobailii went through remarkably parallel but independent steps to regain fertility after they were formed by separate inter species hybridizations.

TL;DR: It is proposed that the functional specialization of Sir3, itself a paralog of Orc1, as a silencing protein was facilitated by the tandem duplication of the OIR domain in the Sir1 family, allowing distinct Sir1–Sir3 and Sir1-Orc1 interactions through OIR–BAH domain interactions.

TL;DR: It is shown that DUR31 (an ortholog of N. crassa gene NCU01977) encodes a thiamin transporter in Candida species, and that the functional elements of the riboswitch are contained within the native intron of Dur31 from Candida parapsilosis, andthat the Riboswitch regulates splicing in aThiamin-dependent manner when RFP is constitutively expressed.

TL;DR: The HTN1 protein may interact with yeast GSP1, GSP2, and PRP20 proteins in an intracellular signalling pathway equivalent to the mammalian RanBP1-Ran/TC4-RCC1 pathway.