K
Kenneth H. Wolfe
Researcher at University College Dublin
Publications - 206
Citations - 50461
Kenneth H. Wolfe is an academic researcher from University College Dublin. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 80, co-authored 195 publications receiving 47190 citations. Previous affiliations of Kenneth H. Wolfe include University of Texas Health Science Center at Houston & University of Sydney.
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Journal ArticleDOI
Coverage-Versus-Length Plots, a Simple Quality Control Step for de Novo Yeast Genome Sequence Assemblies.
Alexander P Douglass,Caoimhe E. O’Brien,Benjamin Offei,Aisling Y. Coughlan,Raúl A. Ortiz-Merino,Geraldine Butler,Kevin P. Byrne,Kenneth H. Wolfe +7 more
TL;DR: G graphing the information that SPAdes provides about the length and coverage of each scaffold can be used to investigate the nature of an assembly, and to diagnose possible problems, and a Python script is provided that allows assemblies to be filtered to remove contaminants identified in CVL plots.
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Small single-copy region of plastid DNA in the non-photosynthetic angiosperm Epifagus virginiana contains only two genes. Differences among dicots, monocots and bryophytes in gene organization at a non-bioenergetic locus.
TL;DR: In this article, the nucleotide sequence of a 7 kb (1 kb = 10 3 base-pairs) region that includes the entire small single-copy region (SSC) of the plastid genome of Epifagus virginiana, a non-photosynthetic, parasitic flowering plant, was determined.
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Evolution of the plastid ribosomal RNA operon in a nongreen parasitic plant: accelerated sequence evolution, altered promoter structure, and tRNA pseudogenes.
TL;DR: The nucleotide sequence of a 7.4 kb region containing the entire plastid ribosomal RNA operon of the nongreen parasitic plant Epifagus virginiana has been determined and analysis of the sequence indicates that all four rRNA genes are intact and almost certainly functional.
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Multiple Reinventions of Mating-type Switching During Budding Yeast Evolution
Tadeusz Krassowski,Jacek Kominek,Xing-Xing Shen,Dana A. Opulente,Dana A. Opulente,Xiaofan Zhou,Antonis Rokas,Chris Todd Hittinger,Chris Todd Hittinger,Kenneth H. Wolfe +9 more
TL;DR: It is found that mating-type switching has arisen independently at least 11 times during yeast evolution and that transitions from heterothallism to homothallistan greatly outnumber transitions in the opposite direction.
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Rewiring the transcriptional regulatory circuits of cells
TL;DR: New data from yeast species show that both processes that regulate gene expression can happen, by changing the cis-acting DNA elements in promoters, or by replacing the trans-acting regulatory proteins.