Kevin K. Tsia

TL;DR: This work maps a two-dimensional (2D) image into a serial time-domain data stream and simultaneously amplifies the image in the optical domain and overcomes the compromise between sensitivity and frame rate without resorting to cooling and high-intensity illumination.

TL;DR: In this paper, the authors present a theory of ADFT by deriving the general equation and spectral resolution for ADFT and studying the evolution of the pulse spectrum into time, the effect of GVD coefficients on ADFT, and the requirement for dispersion.

TL;DR: Serial time-encoded amplified microscopy (STEAM) is a new high-sensitivity ultrafast real-time imaging modality and an analysis of its spatial resolution, frame rate, and detection sensitivity is described.

TL;DR: This work presents a new pulse-stretching technique, termed free-space angular-chirp-enhanced delay (FACED), with three distinguishing features absent in the prevailing dispersive-fiber-based implementations, and demonstrates not only ultrafast laser-scanning time-stretch imaging with superior bright-field image quality compared with previous work but also, for the first time, MHz fluorescence and colorized time-Stretch microscopy.

TL;DR: High-speed two-photon laser scanning microscopy using a passive laser scanner based on free-space angular-chirp-enhanced delay achieves frame rates suitable for voltage imaging in vivo in the mouse brain.